A spiking network model that examines the transformation of odor information from olfactory bulb to piriform cortex demonstrates how intrinsic cortical circuitry preserves representations of odor identity across odorant concentrations.
Dendrites of pyramidal neurons in piriform cortex can initiate NMDA spikes, which may serve to amplify odor responses, and provide combination selectivity underlying 'discontinuous' odor receptive fields in these neurons.
Intracortical circuits in mouse olfactory cortex stabilize odor-evoked activity patterns when upstream inputs, from olfactory bulb, become degraded under anesthesia.
Delay-period activity of anterior piriform cortex is important for working memory tasks requiring active maintenance and encodes the maintained information.
Pharmacological fMRI reveals that associative connections contribute to odor categorization by supporting discrimination and generalization at different stages of the human olfactory system.
Different features of an odor can be represented in mouse olfactory cortex using the particular ensemble of responsive neurons to represent odor identity and the synchrony of the ensemble activity to represent odor intensity.
Computational models and software connect metagenomics to metabolic network reconstruction, assess metabolic complementarity between species, and identify critical species associated to functions of interest.
Human primary olfactory cortical regions can be parcellated into anatomically distinct areas based on whole-brain functional connectivity profiles, suggesting distinct, parallel functional pathways in the human olfactory system.