3,247 results found
    1. Neuroscience

    Event boundaries drive norepinephrine release and distinctive neural representations of space in the rodent hippocampus

    Sam McKenzie, Alexandra L Sommer ... Daniel F English
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics

    Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling

    Nevin K Zacharia, Stefanie Kuhns ... Esben Lorentzen
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Cancer Biology

    Deuterium Metabolic Imaging Phenotypes Mouse Glioblastoma Heterogeneity Through Glucose Turnover Kinetics

    Rui V Simões, Rafael N Henriques ... Noam Shemesh
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Simulation-based survey of TMEM16 family reveals that robust lipid scrambling requires an open groove

    Christina A Stephens, Niek van Hilten ... Michael Grabe
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Inadequate
    1. Neuroscience

    Cortical dynamics in hand/forelimb S1 and M1 evoked by brief photostimulation of the mouse’s hand

    Daniela Piña Novo, Mang Gao ... Gordon MG Shepherd
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Supralinear dendritic integration in murine dendrite-targeting interneurons

    Simonas Griesius, Amy Richardson, Dimitri Michael Kullmann
    NMDA receptors mediate prominent supralinear summation of clustered excitatory inputs to the dendrites of neurogliaform and oriens-lacunosum moleculare interneurons of the hippocampus, showing that these cells perform sub-cellular computations.
    1. Neuroscience

    Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum

    Silas E Busch, Christian Hansel
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Glia control experience-dependent plasticity in an olfactory critical period

    Hans C Leier, Alexander J Foden ... Heather T Broihier
    A Drosophila olfactory circuit exhibits experience-dependent glial pruning during a well-defined critical period, with long-term consequences for odor processing.
    1. Medicine
    2. Neuroscience

    Cold induces brain region-selective cell activity-dependent lipid metabolism

    Hyeonyoung Min, Yale Y Yang, Yunlei Yang
    It is of significance in identifying temperature sensitive brain regions in brain energy metabolism, as which might provide potential targetable sites in the treatment of brain lipid metabolism-associated neurological disorders.
    1. Neuroscience

    Nutritional state-dependent modulation of insulin-producing cells in Drosophila

    Rituja S Bisen, Fathima Mukthar Iqbal ... Jan M Ache
    An in vivo electrophysiology approach identifies an incretin-like effect in Drosophila insulin-producing cells, highlighting key circuit dynamics which govern glucose homeostasis via conserved mechanisms.

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