3,830 results found
    1. Neuroscience

    Extracting grid cell characteristics from place cell inputs using non-negative principal component analysis

    Yedidyah Dordek et al.
    Computational modeling of the brain’s navigation system reveals that place cells can drive the formation of hexagonal patterns experimentally observed in grid cells activity.
    1. Neuroscience

    Hippocampal place cells construct reward related sequences through unexplored space

    H Freyja Ólafsdóttir et al.
    In anticipation of a reward, hippocampal place cells simulate desired journeys through areas that have been seen, but not explored.
    1. Neuroscience

    Social observation enhances cross-environment activation of hippocampal place cell patterns

    Xiang Mou, Daoyun Ji
    Place cells associated with track-running are activated in rats staying in a nearby box while another rat running on the track, suggesting that social observation facilitates spatial memory representations.
    1. Neuroscience

    Place cells on a maze encode routes rather than destinations

    Roddy M Grieves et al.
    Place cells in the rat hippocampus encode positions along well-learned routes as opposed to intended destinations.
    1. Neuroscience

    Episodic-like memory trace in awake replay of hippocampal place cell activity sequences

    Susumu Takahashi
    What will happen where and when could be predicted by the sequential reactivation of place cells that occurs while an animal pauses, suggesting that the replay is linked to mental time travel.
    1. Developmental Biology and Stem Cells

    The invariant cleavage pattern displayed by ascidian embryos depends on spindle positioning along the cell's longest axis in the apical plane and relies on asynchronous cell divisions

    Rémi Dumollard et al.
    Cell cycle asynchrony regulates apical cell shape to drive cell division orientation in the apical plane.
    1. Developmental Biology and Stem Cells

    Dynamic transcriptional signature and cell fate analysis reveals plasticity of individual neural plate border cells

    Daniela Roellig et al.
    The vertebrate neural plate border is comprised of precursors that coexpress multiple lineage markers and small changes in their levels can bias border cell fate.
    1. Cell Biology

    The equatorial position of the metaphase plate ensures symmetric cell divisions

    Chia Huei Tan et al.
    Human cells center the position of the metaphase plate before anaphase onset to ensure the formation of equal-sized daughter cells.
    1. Neuroscience

    Activities of visual cortical and hippocampal neurons co-fluctuate in freely moving rats during spatial behavior

    Daniel Christopher Haggerty, Daoyun Ji
    As rats learn to traverse back and forth on a track, visual cortical neurons fire at specific locations and functionally interact with those hippocampal place cells representing the same locations.
    1. Neuroscience

    Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors

    Alessandro Papale et al.
    Two cell-penetrating peptides that inhibit Ras-ERK signalling and a potent clinically relevant MEK inhibitor block cocaine conditioned place preference and accelerate extinction of cocaine self-administration upon a single administration in mice.

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