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    1. Neuroscience

    Episodic-like memory trace in awake replay of hippocampal place cell activity sequences

    Susumu Takahashi
    What will happen where and when could be predicted by the sequential reactivation of place cells that occurs while an animal pauses, suggesting that the replay is linked to mental time travel.
    1. Neuroscience

    ‘Fearful-place’ coding in the amygdala-hippocampal network

    Mi-Seon Kong, Eun Joo Kim ... Jeansok J Kim
    By recording simultaneous spike trains from fear-responsive basal amygdala (BA) and place-responsive dorsal hippocampus (dHPC) neurons in rats foraging for food in a risky predatory situation, a novel BA-dHPC circuit coding mechanism for interfacing danger and place information was revealed.
    1. Neuroscience

    Learning place cells, grid cells and invariances with excitatory and inhibitory plasticity

    Simon Nikolaus Weber, Henning Sprekeler
    A large variety of spatial representations implied in rodent navigation could arise robustly and rapidly from inputs with a weak spatial structure, by an interaction of excitatory and inhibitory synaptic plasticity.
    1. Developmental Biology

    An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis

    Haoran Zhang, Li Wang ... Mai Har Sham
    Dephosphorylation of Notch1 intracellular domain by Eya1 leads to enhanced Notch signalling activity in the non-neuronal epibranchial placodal cells, revealing an essential regulation for the formation of proximal pharyngeal arches during mouse craniofacial development.
    1. Neuroscience

    Cholinergic modulation shifts the response of CA1 pyramidal cells to depolarizing ramps via TRPM4 channels with potential implications for place field firing

    Crescent L Combe, Carol M Upchurch ... Sonia Gasparini
    A nonspecific cation current mediated by TRPM4 channels is a major contributor to the increase in excitability induced by cholinergic modulation in hippocampal CA1 pyramidal neurons, which are thought to play an important role in episodic memory.
    1. Neuroscience

    Social observation enhances cross-environment activation of hippocampal place cell patterns

    Xiang Mou, Daoyun Ji
    Place cells associated with track-running are activated in rats staying in a nearby box while another rat running on the track, suggesting that social observation facilitates spatial memory representations.
    1. Neuroscience

    Rhythmic coordination and ensemble dynamics in the hippocampal-prefrontal network during odor-place associative memory and decision making

    Claire A Symanski, John H Bladon ... Shantanu P Jadhav
    A novel mechanism of long-range coordination mediated by beta oscillations across sensory and cognitive netowrks for utilization of odor-cued associations and translating them into decisions.
    1. Developmental Biology

    Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor

    Arun Devotta, Hugo Juraver-Geslin ... Jean-Pierre Saint-Jeannet
    A combination of morpholino-based knockdowns, pharmacological inhibitors, and rescue assays reveal a novel role for natriuretic peptide signaling in the regulation of cell fates in the embryonic ectoderm.
    1. Epidemiology and Global Health

    Ebola virus disease in the Democratic Republic of the Congo, 1976-2014

    Alicia Rosello, Mathias Mossoko ... Jean-Jacques Muyembe Tamfum
    Analysing a compilation of individual-level data gathered across the seven Ebola Virus Disease outbreaks in the Democratic Republic of the Congo reveals factors that contribute to the spread of the disease and mortality.
    1. Neuroscience

    Intrinsic dynamics of randomly clustered networks generate place fields and preplay of novel environments

    Jordan Breffle, Hannah Germaine ... Paul Miller
    Computational simulations and data analysis show that random clustering in the connections of neurons receiving minimal external cues can generate place fields and their spontaneous activation in trajectory-like sequences.