The planarian mex3-1 gene is required for non-stem cell fates and suppresses a stem cell fate in differentiating cells.

Planarian brain neurons modulate their turnover by signaling to nearby stem cells.

A gene expression-guided functional screen identifies factors and cell types that regulate diverse aspects of neural regeneration in planarians.

Hedgehog signaling plays a role in regulating glia gene expression in planarians, pointing to a candidate ancestral and broadly used role for the Hedgehog pathway.

Homeostatic tissue maintenance can occur at locations distinct from the target sites of organ regeneration planarians.

A conserved alternative splicing program is specific to planarian stem cells and is controlled by the highly conserved splicing factors CELF and MBNL; therefore, this mode of regulating stem cells is likely ancestral to all animals.

A combination of experimental and theoretical analysis identifies body size-dependent energy storage as the physiological cause of 3/4-power law scaling of the metabolic rate in planarians.

Single-cell RNA sequencing identifies an adult regional gene expression map in planarian muscle that includes two FGFRL-Wnt circuits controlling head and trunk tissue pattern.

Physiological porphyrin biosynthesis causes photosensitivity in fasted planarians, providing an experimentally tractable animal model of acute porphyrias.