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Repurposing continuous integration tools for scientific analyses takes the headache out of reproducible research.
eLife-News - First eLife articles published, media policy announced, plans for #ASCB2012
The Natural History of Model Organisms
Edited by Ian Baldwin et al.
Essays on the wild lives of model organisms, from
to the zebrafish.
Episode 64: February 2020
In this episode we hear about genetic privacy, plants with three parents, using cannabis to treat endometriosis, a new type of hearing test and how we can enjoy a cuddle.
Edited by Emma Pewsey et al.
On the last Wednesday of each month, members of the eLife Early-Career Advisory Group invite experts to share their views and advice on subjects pertinent to research careers.
Physics of Living Systems
Epithelial colonies in vitro elongate through collective effects
Jordi Comelles et al.
Spontaneous elongation of epithelial colonies is related to the orientation of the mean nematic cell elongation field, as shown and tested with experiments and theory.
Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders
Helen Wong et al.
Murine behavioral testing and biochemical experiments reveal AKT isoform- and sex-dependent mechanisms regulating affective behavior, memory formation, and extinction.
Genetics and Genomics
Systematic identification of
-regulatory variants that cause gene expression differences in a yeast cross
Kaushik Renganaath et al.
Yeast promoters can harbor multiple natural DNA variants that influence gene expression, interact genetically, evolve under negative selection, alter transcription factor motifs, and remain challenging to predict.
Canonical goal-selective representations are absent from prefrontal cortex in a spatial working memory task requiring behavioral flexibility
Claudia Böhm, Albert K Lee
Representation of goals in the forms previously reported in the PFC is not required for performance of a novel spatial working memory task where goal information must be used flexibly.
Biochemistry and Chemical Biology
Synergy between Wsp1 and Dip1 may initiate assembly of endocytic actin networks
Connor J Balzer et al.
An activator of branching nucleation by Arp2/3 complex directly synergizes with an activator of linear filament nucleation to initiate assembly of actin networks that drive endocytosis.
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