416 results found
    1. Cancer Biology
    Reproducibility Project

    Reproducibility Project: Cancer Biology

    Curated by Roger J Davis et al.
    Investigating reproducibility in preclinical cancer research.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease
    Tropical disease

    Tropical Disease: A Collection of Articles

    Curated by Prabhat Jha et al.
    eLife has published papers on many tropical diseases, including malaria, Ebola, leishmaniases, Dengue and African sleeping sickness.
  1. May 2014

    Episode 12: May 2014

    In this episode we hear about the neuroscience of chewing, skin cancer, African sleeping sickness, an ancient protein complex, and our editor-in-chief shares his thoughts on scientific publishing.
  2. July 2013

    Episode 2: July 2013

    In this episode we hear about plants doing maths, the evolution of cancer, why blood vessels don'€™t grow in the retina, the immune system and more.
    1. Developmental Biology
    2. Human Biology and Medicine

    Type XVII collagen coordinates proliferation in the interfollicular epidermis

    Mika Watanabe et al.
    Type XVII collagen, a transmembranous protein in basal keratinocytes, suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Microbiota regulates visceral pain in the mouse

    Pauline Luczynski et al.
    Determining that microbiota-deficient mice have increased visceral pain, which can be reversed by restoring microbiota, may lead to novel microbial-based strategies for disorders associated with visceral pain.
    1. Cell Biology
    2. Developmental Biology

    Macrophages are necessary for epimorphic regeneration in African spiny mice

    Jennifer Simkin et al.
    Inflammatory cells differentially regulate a scarring versus a regenerating response to injury in mammals.
    1. Chromosomes and Gene Expression

    Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis

    Candice L Wike et al.
    A histone modification that alters the nucleosome structure occurs in mitosis and promotes chromosome packaging and the timely removal of condensin I and cohesion, to achieve chromosome segregation.
    1. Cell Biology

    Centriolar SAS-7 acts upstream of SPD-2 to regulate centriole assembly and pericentriolar material formation

    Kenji Sugioka et al.
    A genetic screen and live cell imaging show that a newly identified coiled-coil protein called SAS-7 is the earliest acting factor in centriole assembly yet identified in the roundworm Caenorhabditis elegans.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex

    Jordan D Carelli et al.
    An ancient complex comprising the eukaryotic elongation factor-1A and aminoacylated tRNA is shown to be the target of a cyclic heptapeptide and two unrelated natural products with potent anticancer activity.

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