139 results found
    1. Evolutionary Biology
    2. Physics of Living Systems

    Functional biology in its natural context: A search for emergent simplicity

    Joy Bergelson et al.
    The time is right to study biological function without stripping systems of their essential eco-evolutionary context.
    1. Immunology and Inflammation

    Biological controls for standardization and interpretation of adaptive immune receptor repertoire profiling

    Johannes Trück et al.
    The needs and challenges of AIRR-seq controls are presented.
    1. Cell Biology

    A robust method for particulate detection of a genetic tag for 3D electron microscopy

    James Rae et al.
    Development of a new system for gold particle detection of a genetic tag for electron microscopy.
    1. Developmental Biology

    The LRR-TM protein PAN-1 interacts with MYRF to promote its nuclear translocation in synaptic remodeling

    Shi-Li Xia et al.
    Identified as a binding factor of transcription factor MYRF, the LRR-TM protein PAN-1 promotes the cell-membrane localization and nuclear translocation of MYRF, which drives synaptic rewiring in Caenorhabditis elegans.
    1. Ecology
    2. Microbiology and Infectious Disease

    Multiple lineages of Streptomyces produce antimicrobials within passalid beetle galleries across eastern North America

    Rita de Cassia Pessotti et al.
    The widespread occurrence of metabolically active streptomycetes in Odontotaenius disjunctus beetle frass may insulate their galleries against pathogenic fungal invasion through the production of diverse antimicrobial specialized metabolites.
    1. Microbiology and Infectious Disease

    Highly parallelized droplet cultivation and prioritization of antibiotic producers from natural microbial communities

    Lisa Mahler et al.
    This microscale cultivation strategy will help in the discovery of novel bacterial species and their prioritization for antibiotic screening campaigns.
    1. Evolutionary Biology

    Chloroplast acquisition without the gene transfer in kleptoplastic sea slugs, Plakobranchus ocellatus

    Taro Maeda et al.
    The newly opened genome of a kleptoplastic mollusk, Plakobranchus ocellatus, indicated that sequestered plastids retain their activity within the animal cell without horizontal algal gene transfer to the animal nucleus.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    NusG is an intrinsic transcription termination factor that stimulates motility and coordinates gene expression with NusA

    Zachary F Mandell et al.
    The general transcription elongation factor NusG functions as an intrinsic termination factor in Bacillus subtilis and together with NusA coordinates global gene expression including the motility regulon.
    1. Neuroscience

    Analysis of ultrasonic vocalizations from mice using computer vision and machine learning

    Antonio HO Fonseca et al.
    An open-source tool based on computational vision and machine learning shows high accuracy and sensitivity in the analysis of ultrasonic vocalizations.
    1. Ecology
    2. Evolutionary Biology

    Effects of domestication on the gut microbiota parallel those of human industrialization

    Aspen T Reese et al.
    Gut microbial signatures of domestication parallel those of industrialization, implicating shared ecological drivers.

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