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    1. Developmental Biology
    2. Evolutionary Biology

    Early maternal loss leads to short- but not long-term effects on diurnal cortisol slopes in wild chimpanzees

    Cédric Girard-Buttoz et al.
    Wild chimpanzees contrast to humans since adult male chimpanzees do not exhibit physiological indicators of biological embedding of the stress associated to maternal loss early in life.
    1. Medicine

    Infrared molecular fingerprinting of blood-based liquid biopsies for the detection of cancer

    Marinus Huber et al.
    The combination of molecular infrared fingerprinting and machine learning enables the detection of breast, bladder, prostate, and lung cancer based on liquid blood serum and plasma, providing a general framework for the minimally invasive investigation of oncological conditions.
    1. Neuroscience

    Network-wide abnormalities explain memory variability in hippocampal amnesia

    Georgios PD Argyropoulos et al.
    Hippocampal damage is associated with changes across the extended hippocampal system, and these may explain variability in memory between patients presenting with hippocampal amnesia.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation

    David Trombley McSwiggen et al.
    Transient DNA interactions by DNA-binding proteins are utilized by herpes simple virus as an alternative route to generate membraneless compartments in the nucleus without invoking phase separation.
    1. Microbiology and Infectious Disease

    Host genetic selection for cold tolerance shapes microbiome composition and modulates its response to temperature

    Fotini Kokou et al.
    Microbiome and transcriptomic profiling of genetically selected tropical fish with high and low tolerance to cold exposure revealed host control over microbiome composition and response to temperature changes.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity

    Xue-Song Zhang et al.
    Alteration of host gut microbiota by antibiotic exposure in early life remodeled host intestinal immune development and metabolism and enhanced the induction of type 1 diabetes in genetically predisposed animals.
    1. Microbiology and Infectious Disease

    Visualizing trypanosomes in a vertebrate host reveals novel swimming behaviours, adaptations and attachment mechanisms

    Éva Dóró et al.
    The transparent zebrafish reveals the reality of trypanosomes swimming in a vertebrate host, and their adaptations to an extremely heterogenic environment.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    The structure of the COPI coat determined within the cell

    Yury S Bykov et al.
    Cryo-electron tomography of COPI vesicles in the Golgi reveals coat structure, disassembly dynamics, cargo binding, and morphological variability.
    1. Neuroscience

    A neural-level model of spatial memory and imagery

    Andrej Bicanski, Neil Burgess
    The BB model explains spatial cognition in terms of interactions between specific neuronal populations, providing a common computational framework for the human neuropsychological and in vivo animal electrophysiological literatures.
    1. Neuroscience

    Hippocampome.org: a knowledge base of neuron types in the rodent hippocampus

    Diek W Wheeler et al.
    Hippocampome.org is an online resource that provides free human- and machine-readable access to the comprehensive property-based classification of hippocampal neurons from 14,000 pieces of published experimental evidence.