The therapeutic effects of the sleeping pill zolpidem in patients with disorders of consciousness may be due to recruitment of brain cells idling in abnormally low-frequency brain waves.

The overexpression of RNA chaperones, including several DEAD box RNA helicases, enhances the fitness of mutationally compromised E. coli strains.

There is limited epigenetic conservation of lineage-specific DNA elements in Treg cells, and genetic variation in Treg cell specific enhancers is associated with autoimmune disease.

In an investigation into the effects of drugs on proteins, an active machine learning algorithm chose which sets of experiments to perform and was able to learn an accurate model of the effects after doing only a fraction of the experiments.

Visual, parietal, and frontal motor cortices play distinct and necessary roles in mapping sensory features to future motor action.

A screen of tens of thousands of vesicle traffic networks in silico shows that Golgi-like cisternal maturation is a natural outcome of vesicle traffic homeostasis.

Anarchic, cycling piwi-1+ embryonic cells gives rise to neoblasts, pluripotent stemcells required for development of all organ systems during S. mediterranea embryogenesis, as well as the maintenance andregeneration of tissues during adulthood.

Guidelines governing research into embryos need to be updated in a way that reflects the moral status of synthetic human entities generated using the methods of synthetic biology.

An in silico reconstruction of a chloroplast that existed hundreds of millions of years ago casts new insights in the evolutionary processes, endosymbioses and chimerism events that shape the origin of plastids.

The integration of structural data from different imaging scales requires the development of standards and tools for representing the segmentation and transformation of data, and for the annotation of biological structures.