In this episode we hear about the cocktail party effect, the role of psuedogene RNA in the immune response, the genetic origins of a common form of blindness, the flu vaccine, and the origins of schistosomiasis.
Several neuronal subtypes found in the early zebrafish olfactory placode are not derived from the neural crest, as previously thought, but from the preplacodal ectoderm.
The transcription and splicing factor T-box3 is present in primary cilia, regulates multiple aspects of limb development, and interacts with members of the protein complex required for the stability and processing of the Gli3 transcription factor.
Pre-existing enhancers interpret T cell signaling strength in an analogue manner to direct quantitative changes in gene expression within the context of an overall digital response.
KPNB1 regulates rhythmic spatio-temporal nuclear import of the PER/CRY complex and is required for negative feedback repression in mammalian and fly clock function.