6,732 results found
    1. Cell Biology

    PM2.5 leads to adverse pregnancy outcomes by inducing trophoblast oxidative stress and mitochondrial apoptosis via KLF9/CYP1A1 transcriptional axis

    Shuxian Li, Lingbing Li ... Xietong Wang
    Airborne PM2.5 exposure triggers oxidative stress and mitochondrial apoptosis in placental trophoblast cells via the KLF9/CYP1A1 transcriptional axis, ultimately leading to adverse pregnancy outcomes.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Juxtaposition of heterozygous and homozygous regions causes reciprocal crossover remodelling via interference during Arabidopsis meiosis

    Piotr A Ziolkowski, Luke E Berchowitz ... Ian R Henderson
    Heterozygosity changes the balance between interfering and non-interfering crossovers during Arabidopsis meiosis.
    1. Neuroscience

    Perceptual error based on Bayesian cue combination drives implicit motor adaptation

    Zhaoran Zhang, Huijun Wang ... Kunlin Wei
    Model based on Bayesian cue combination shows that procedural motor learning is driven by perceptual error in localizing one's effector.
    1. Neuroscience

    Neural precursors of decisions that matter—an ERP study of deliberate and arbitrary choice

    Uri Maoz, Gideon Yaffe ... Liad Mudrik
    The readiness potential—a long-established neural precursor of voluntary action claimed to precede the onset of the conscious decision to move—is absent, or at least significantly reduced, for deliberate decisions.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into actin isoforms

    Amandeep S Arora, Hsiang-Ling Huang ... Krishna Chinthalapudi
    The functional differences between actin isoforms have been explored through structural studies.
    1. Structural Biology and Molecular Biophysics

    Cadherin clusters stabilized by a combination of specific and nonspecific cis-interactions

    Connor J Thompson, Zhaoqian Su ... Daniel K Schwartz
    A combined experimental and computational approach was developed to understand lateral interactions between membrane-bound proteins and used to quantify the contributions of specific and non-specific interactions to cadherin cis-binding kinetics.
    1. Cancer Biology
    2. Cell Biology

    Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα

    Francesca Butera, Julia E Sero ... Chris Bakal
    A live imaging and computational approach reveals feedback loops involving F-actin dynamics that regulate the NF-κB transcription factor RELA.
    1. Neuroscience

    The nematode worm C. elegans chooses between bacterial foods as if maximizing economic utility

    Abraham Katzen, Hui-Kuan Chung ... Shawn R Lockery
    A worm with a nervous system of only 302 neurons satisfies the necessary and sufficient conditions for value-based decision making.
    1. Neuroscience

    Nucleus accumbens dopamine tracks aversive stimulus duration and prediction but not value or prediction error

    Jessica N Goedhoop, Bastijn JG van den Boom ... Ingo Willuhn
    The extracellular concentration of dopamine in the nucleus accumbens core is progressively diminished by white noise, an underutilized, easy-to-titrate aversive stimulus, but is unaffected by white-noise intensity, context valence, and associated probabilistic contingencies.
    1. Neuroscience
    2. Physics of Living Systems

    Gigapixel imaging with a novel multi-camera array microscope

    Eric E Thomson, Mark Harfouche ... Eva A Naumann
    A new multi camera imaging platform simultaneously captures large-area, high-resolution video of unconstrained small model organisms and provides behavioral measurements that span multiple spatial scales.

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