The prediction accuracies of polygenic scores in humans vary depending on the characteristics of the samples, as well as based on the study design, within a single ancestry group.

A resource to systematically explore the association between overall genetic risk for 162 risk factors and disease with 551 outcomes.

Current polygenic scores for education do not provide accurate predictions of educational achievement above other data or at the individual level.

A study of 3,500 children in the UK shows that data on socioeconomic background and previous educational achievements can better predict how students will perform at school than genetic data.

Great care is needed when interpreting claims about the genetic basis of human variation based on data from genome-wide association studies.

Susceptibility to uterine fibroids, benign tumors that affect the health of many women, is linked to genes that are responsible for preserving genome integrity and promoting genitourinary development.

Two studies suggest that a determined adversary may be able to obtain genetic information that they should not have permission to access from some genealogy databases.

We identify key strengths and limitations in use of viral genotyping and phenotyping to estimate pandemic risk from influenza A viruses, focusing on 3 traits, hemagglutinin binding specificity, hemagglutinin pH of activation, and polymerase complex efficiency.

The single-cell eQTLGen consortium aims to pinpoint the cellular contexts in which disease-causing genetic variants affect gene expression and its regulation.

Mycobacterium tuberculosis exploits an IFN/IL6/CEBP axis linked to monocyte expansion in humans.