138 results found
    1. Genetics and Genomics

    Variable prediction accuracy of polygenic scores within an ancestry group

    Hakhamanesh Mostafavi et al.
    The prediction accuracies of polygenic scores in humans vary depending on the characteristics of the samples, as well as based on the study design, within a single ancestry group.
    1. Genetics and Genomics

    An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

    Tom G Richardson et al.
    A resource to systematically explore the association between overall genetic risk for 162 risk factors and disease with 551 outcomes.
    1. Genetics and Genomics

    Can education be personalised using pupils’ genetic data?

    Tim T Morris et al.
    Current polygenic scores for education do not provide accurate predictions of educational achievement above other data or at the individual level.
    1. Genetics and Genomics

    Polygenic Scores: It is time to get real when trying to predict educational performance

    Cecile Janssens
    A study of 3,500 children in the UK shows that data on socioeconomic background and previous educational achievements can better predict how students will perform at school than genetic data.
    Insight
    Available as:
    • HTML
    • PDF
    1. Evolutionary Biology
    2. Genetics and Genomics

    Population Genetics: Why structure matters

    Nick Barton et al.
    Great care is needed when interpreting claims about the genetic basis of human variation based on data from genome-wide association studies.
    Insight
    Available as:
    • HTML
    • PDF
    1. Genetics and Genomics

    Genome-wide Association Study: Not so benign

    Barbara Rivera
    Susceptibility to uterine fibroids, benign tumors that affect the health of many women, is linked to genes that are responsible for preserving genome integrity and promoting genitourinary development.
    Insight
    Available as:
    • HTML
    • PDF
    1. Evolutionary Biology
    2. Genetics and Genomics

    Genealogy: The challenges of maintaining genetic privacy

    Shai Carmi
    Two studies suggest that a determined adversary may be able to obtain genetic information that they should not have permission to access from some genealogy databases.
    Insight
    Available as:
    • HTML
    • PDF
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Science Forum: Viral factors in influenza pandemic risk assessment

    Marc Lipsitch et al.
    We identify key strengths and limitations in use of viral genotyping and phenotyping to estimate pandemic risk from influenza A viruses, focusing on 3 traits, hemagglutinin binding specificity, hemagglutinin pH of activation, and polymerase complex efficiency.
    1. Genetics and Genomics

    Science Forum: The single-cell eQTLGen consortium

    MGP van der Wijst et al.
    The single-cell eQTLGen consortium aims to pinpoint the cellular contexts in which disease-causing genetic variants affect gene expression and its regulation.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans

    Murilo Delgobo et al.
    Mycobacterium tuberculosis exploits an IFN/IL6/CEBP axis linked to monocyte expansion in humans.

Refine your results by:

Type
Research categories