13,166 results found
    1. Evolutionary Biology
    2. Genetics and Genomics

    On the limits of fitting complex models of population history to f-statistics

    Robert Maier, Pavel Flegontov ... David Reich
    Many published findings about population history that rely on inference of admixture graph models fitted to f-statistics are not robust since the method is generally inappropriate for extracting new information about population history.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Heterogeneous absorption of antimicrobial peptide LL37 in Escherichia coli cells enhances population survivability

    Mehdi Snoussi, John Paul Talledo ... Sattar Taheri-Araghi
    A rapid absorption and retention of antimicrobial peptides by dead Escherichia coli cells can increase the survivability of the cell population in a "cooperative" fashion.
    1. Evolutionary Biology

    Native American genetic ancestry and pigmentation allele contributions to skin color in a Caribbean population

    Khai C Ang, Victor A Canfield ... Keith C Cheng
    Analysis of 458 Kalinago provides new insights into the population's genetic structure, the contribution of Native American ancestry to skin pigmentation, and the identification of a coding variant in OCA2 with an estimated –8 melanin units effect size.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Rapid adaptation to malaria facilitated by admixture in the human population of Cabo Verde

    Iman Hamid, Katharine L Korunes ... Amy Goldberg
    Admixture-mediated adaptation to malaria in a human population demonstrates that detectible signatures in genomic patterns of ancestry can be leveraged to better characterize recent selection in populations with mixed ancestry.
    1. Neuroscience

    Local field potentials reflect cortical population dynamics in a region-specific and frequency-dependent manner

    Cecilia Gallego-Carracedo, Matthew G Perich ... Juan Álvaro Gallego
    There is a frequency-dependent association between the local field potential and the coordinated activity of populations of single neurons, which remains constant during different aspects of behaviour but changes across regions of primate sensorimotor cortex.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A population-level invasion by transposable elements triggers genome expansion in a fungal pathogen

    Ursula Oggenfuss, Thomas Badet ... Daniel Croll
    The activation of transposable elements and relaxed purifying selection underpin an incipient expansion of the genome in populations of a major wheat pathogen.
    1. Neuroscience

    Population receptive fields in nonhuman primates from whole-brain fMRI and large-scale neurophysiology in visual cortex

    P Christiaan Klink, Xing Chen ... Pieter R Roelfsema
    Within-species comparison of population receptive fields determined with fMRI and electrophysiology in nonhuman primates reveals the neuronal basis of blood-oxygen-level-dependent-based retinotopy.
    1. Ecology
    2. Evolutionary Biology

    CRISPR-based herd immunity can limit phage epidemics in bacterial populations

    Pavel Payne, Lukas Geyrhofer ... Jonathan P Bollback
    Bacteria can exhibit herd immunity protection against phages, which may play a significant role in their ecology and evolution.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Intra-species differences in population size shape life history and genome evolution

    David Willemsen, Rongfeng Cui ... Dario Riccardo Valenzano
    Population genetics in turquoise killifish wild populations reveals how small population size and genetic drift determine the accumulation of deleterious gene variants leading to short lifespan.
    1. Evolutionary Biology
    2. Medicine

    APOE4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical Amerindian subsistence population

    Angela R Garcia, Caleb Finch ... Benjamin C Trumble
    The relationship between APOE genotype and disease risks may be environmentally moderated, with APOE4 being less harmful and unlikely to increase cardiometabolic risk in a physically active, energy-limited population.

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