Browse the search results

Page 2 of 574
    1. Neuroscience

    Incomplete vesicular docking limits synaptic strength under high release probability conditions

    Gerardo Malagon, Takafumi Miki ... Alain Marty
    The probability of occupancy of individual synaptic release sites at rest sets an upper limit to synaptic output when increasing action potential related calcium entry.
    1. Genetics and Genomics

    Variable prediction accuracy of polygenic scores within an ancestry group

    Hakhamanesh Mostafavi, Arbel Harpak ... Molly Przeworski
    The prediction accuracies of polygenic scores in humans vary depending on the characteristics of the samples, as well as based on the study design, within a single ancestry group.
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains

    Artur Meller, Jeffrey M Lotthammer ... Gregory R Bowman
    A cryptic pocket in the myosin motor domain selectively opens in molecular dynamics simulations, and the probability of pocket opening is predictive of how potently a compound will inhibit a particular myosin motor.
    1. Neuroscience

    Contribution of correlated noise and selective decoding to choice probability measurements in extrastriate visual cortex

    Yong Gu, Dora E Angelaki, Gregory C DeAngelis
    Addressing the controversy regarding the interpretation of choice probabilities demonstrates that both readout strategy and noise correlations contribute to the link between neural activity and perceptual decisions.
    1. Neuroscience

    ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains

    Richard G Held, Changliang Liu, Pascal S Kaeser
    The presynaptic active zone protein ELKS provides synapse-specific control of the pool of readily releasable vesicles and release probability.
    1. Neuroscience

    Cue-inhibited ventrolateral periaqueductal gray neurons signal fear output and threat probability in male rats

    Kristina M Wright, Thomas C Jhou ... Michael A McDannald
    Ventrolateral periaqueductal gray neurons signal fear output through patterned inhibition of neural activity.
    1. Neuroscience

    Proteolytic maturation of α2δ controls the probability of synaptic vesicular release

    Laurent Ferron, Ivan Kadurin, Annette C Dolphin
    Proteolytic maturation of auxiliary α2δ subunits of voltage-gated calcium channels increases neuronal communication by controlling the synaptic release of neurotransmitter.
    1. Neuroscience

    Stimulus-dependent relationships between behavioral choice and sensory neural responses

    Daniel Chicharro, Stefano Panzeri, Ralf M Haefner
    New stimulus-dependencies of choice-related signals in sensory neurons uncovered by new analytical results and methods.
    1. Neuroscience

    Neural structure mapping in human probabilistic reward learning

    Fabrice Luyckx, Hamed Nili ... Christopher Summerfield
    During learning, human neural codes for experienced reward probability map onto the same mental number line for symbolic numbers.
    1. Neuroscience

    Neural basis of somatosensory target detection independent of uncertainty, relevance, and reports

    Pia Schröder, Timo Torsten Schmidt, Felix Blankenburg
    Neural correlates of somatosensory target detection are restricted to secondary somatosensory cortex, whereas activity in insular, cingulate, and motor regions reflects stimulus uncertainty and overt reports.