Vast regions of facultative heterochromatin marked by methylation of lysine 27 on histone H3 depend on their proximity to chromosome ends and can be induced ectopically by insertion of telomere repeats.

Identification of novel components and regulators of heterochromatin reveals a spatially complex and dynamic organization.

Memory over 24 hours was impaired in Parkinson's patients off, rather than on, dopaminergic medication during reinforcement learning, whereas dopamine did not affect positive and negative reinforcement, in contrast to previous studies.