Conditional genetic inactivation of a highly conserved, ancestral subgroup of 14-3-3 proteins in Arabidopsis thaliana reveals fundamental roles in auxin transport-dependent plant development and post-Golgi trafficking processes.
Analysis of Chlamydomonas, planaria and mice reveals a novel and unanticipated role for a peptide amidating enzyme in primary and motile ciliary assembly through effects on post-Golgi trafficking.
Regulation of cellular properties such as ligand secretion and migratory ability through changes in the cytoskeleton mediated by a Wnt5a–Ror2–Vangl2 axis is a major determinant of alveolar formation.
The co-chaperone CHORDC1 is specifically required for epidermal growth factor receptor trafficking and signaling in Caenorhabditis elegans and in human cells.
