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  1. Research: Publication bias and the canonization of false facts

    Silas Boye Nissen et al.
    Publication bias, in which positive results are preferentially reported by authors and published by journals, can restrict the visibility of evidence against false claims and allow such claims to be canonized inappropriately as facts.
    1. Computational and Systems Biology

    Meta-Research: Centralized scientific communities are less likely to generate replicable results

    Valentin Danchev et al.
    Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.
    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic et al.
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.
    1. Cancer Biology

    Reproducibility in Cancer Biology: The challenges of replication

    Interpreting the first results from the Reproducibility Project: Cancer Biology requires a highly nuanced approach.
    Editorial
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  2. Point of View: Overflow in science and its implications for trust

    Sabina Siebert et al.
    Interviews with senior biomedical researchers reveal a perceived decline in trust in the scientific enterprise, in large part because the quantity of new data exceeds the field's ability to process it appropriately.
    1. Computational and Systems Biology

    Cutting Edge: Anatomy of BioJS, an open source community for the life sciences

    Guy Yachdav et al.
    Community nurturing is the single most important factor in determining the sustainability of an open source project such as BioJS.
  3. Point of View: Correcting the bias against interdisciplinary research

    Ehud Shapiro
    When making decisions about funding and jobs the scientific community should recognise that most of the tools used to evaluate scientific excellence are biased in favour of established disciplines and against interdisciplinary research.
  4. Careers: eLife and early career researchers

    Randy Schekman et al.
    There are many reasons for submitting your best work to eLife, especially if you are an early career researcher.
    Editorial
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  5. Meta-Research: Large-scale language analysis of peer review reports

    Ivan Buljan et al.
    The linguistic characteristics of peer review reports are not influenced by research area, type of review or reviewer gender, which is evidence for the robustness of peer review.
  6. Research Culture: Actionable recommendations from trainees to improve science training

    Stephanie M Davis et al.
    Early-career researchers propose seven actions that can be taken by research institutions and departments to improve science training.