The general transcription elongation factor NusG functions as an intrinsic termination factor in Bacillus subtilis and together with NusA coordinates global gene expression including the motility regulon.
Cell-type-specific circuit analysis reveals a highly polysynaptic pattern of excitatory feedforward connections along the somatosensory-to-motor loop, from cuneate via VPL thalamus to S1 and M1 cortex and corticospinal neurons.
Statistical analysis and LASSO regression modeling provide insights into pathogen-specific host response patterns in cerebrospinal fluid from different disease etiologies to support future classification of pathogen type based on host response patterns in meningitis.
The transcription factor (TF)-binding specificities of Pseudomonas aeruginosa allow us to predict virulence-associated TFs and their target genes, which will facilitate to find effective treatment and prevention for its associated diseases.
aDNA revealed a model of domestication where an ancient guanaco population no longer exists, the loss of the ancient vicuña genetic variation in the modern populations, and frequently interbreeding practices.