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    1. Evolutionary Biology

    Recent shifts in the genomic ancestry of Mexican Americans may alter the genetic architecture of biomedical traits

    Melissa L Spear et al.
    Admixture dynamics have recently changed over time in Mexican Americans resulting in an impact on the genetic architecture of phenotypic variation.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Global distribution maps of the leishmaniases

    David M Pigott et al.
    Maps defining environmental risk of the leishmaniases provide insights into the ecology of these diseases and identify regions to target public health measures and inform future burden estimates.
    1. Epidemiology and Global Health

    Vitamin A supplements, routine immunization, and the subsequent risk of Plasmodium infection among children under 5 years in sub-Saharan Africa

    Maria-Graciela Hollm-Delgado et al.
    An analysis of national survey data shows that vitamin A might protect against malaria infection, an effect potentially modified by seasonality, and that no routine vaccinations were linked to parasitemia, though BCG vaccination was associated with PfHRP-2 antigenemia.
    1. Ecology

    Modelling the climatic suitability of Chagas disease vectors on a global scale

    Fanny E Eberhard et al.
    The global ensemble forecasting niche modelling of 11 vector competent triatomine species revealed climatic suitable regions outside their native distribution including the cosmopolitan vector Triatoma rubrofasciata.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Zika seroprevalence declines and neutralizing antibodies wane in adults following outbreaks in French Polynesia and Fiji

    Alasdair D Henderson et al.
    A combination of eight serological surveys shows a decline in seroprevalence over a two-year period following the first reports of Zika transmission in Fiji and French Polynesia.
    1. Epidemiology and Global Health

    A modular approach to integrating multiple data sources into real-time clinical prediction for pediatric diarrhea

    Ben J Brintz et al.
    Using a modular approach to integrate multiple data sources for the prediction of diarrhea etiology has the potential to reduce inappropriate antibiotics prescription in low-resource settings.
    1. Epidemiology and Global Health

    A case study for a psychographic-behavioral segmentation approach for targeted demand generation in voluntary medical male circumcision

    Sema K Sgaier et al.
    A novel, hybrid segmentation technique reveals human heterogeneity in barriers towards a behavior, and is applied to characterize distinct segments in voluntary medical male circumcision.
    1. Epidemiology and Global Health

    Efficacy profile of the CYD-TDV dengue vaccine revealed by Bayesian survival analysis of individual-level phase III data

    Daniel J Laydon et al.
    Bayesian survival analysis reveals comprehensive efficacy profile and mechanism of action for Sanofi-Pasteur’s CYD-TDV dengue vaccine, whereby vaccination acts as a silent, disease-free infection enhancing disease risk in seronegatives, but giving greater immunity in seropositives than two natural infections.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes

    Nimisha Chaturvedi et al.
    Integrated analysis of IFN-λ and HCV amino acid variation indicates the key role of host innate immunity in viral control.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Integrating between-host transmission and within-host immunity to analyze the impact of varicella vaccination on zoster

    Benson Ogunjimi et al.
    An individual-based model estimates exogenous boosting of immunity following re-exposure to chickenpox is limited to 2 years after re-exposure, but an increase in herpes zoster incidence is still expected to occur following universal varicella vaccination.