9,364 results found
    1. Microbiology and Infectious Disease

    The Mla pathway in Acinetobacter baumannii has no demonstrable role in anterograde lipid transport

    Matthew J Powers et al.
    An outer membrane vesicle pulse-chase assay demonstrates that the Acinetobacter baumannii Mla system is a retrograde lipid transporter.
    1. Genetics and Genomics

    Firefly genomes illuminate parallel origins of bioluminescence in beetles

    Timothy R Fallon et al.
    The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.
    1. Medicine

    Research: Adequate statistical power in clinical trials is associated with the combination of a male first author and a female last author

    Willem M Otte et al.
    An analysis of 31,873 clinical trials shows that adequate statistical power was most often present in trials with a male first author and a female last author.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Global biogeographic sampling of bacterial secondary metabolism

    Zachary Charlop-Powers et al.
    Pyro-sequencing of two genes involved in bacterial secondary metabolism provides new insights into the rich reservoir of biologically active small molecules found in environmental bacteria.
    1. Evolutionary Biology
    2. Medicine

    APOE4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical Amerindian subsistence population

    Angela R Garcia et al.
    The relationship between APOE genotype and disease risks may be environmentally moderated, with APOE4 being less harmful and unlikely to increase cardiometabolic risk in a physically active, energy-limited population.
    1. Neuroscience

    Alpha/beta power decreases track the fidelity of stimulus-specific information

    Benjamin James Griffiths et al.
    Neural representations of stimulus-specific information increase in fidelity as the power of alpha/beta activity decreases, suggesting that alpha/beta power decreases reflect a domain-general mechanism that supports information representation.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision

    James A Watson et al.
    Complete blood count data can increase the accuracy of the diagnosis of severe malaria in children in high transmission settings.
    1. Ecology
    2. Evolutionary Biology

    Sexual dimorphism in trait variability and its eco-evolutionary and statistical implications

    Susanne RK Zajitschek et al.
    Sex differences in trait variability imply that both sexes should be included in biomedical trials, using sex-specific statistical power calculations.
    1. Neuroscience

    Resting-state gamma-band power alterations in schizophrenia reveal E/I-balance abnormalities across illness-stages

    Tineke Grent-'t-Jong et al.
    Resting-state MEG-activity and MRS-GABA/Glx measurements reveal that there is a significant shift in excitability during the course of schizophrenia, involving hyperexcitability during the onset and a reduction at chronic stages.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    A community-maintained standard library of population genetic models

    Jeffrey R Adrion et al.
    The stdpopsim library, a community-driven open source project, is presented which provides easy access to a standard catalog of published simulation models for population genetics aimed at field-wide standardization.

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