492 results found
    1. Physics of Living Systems

    Body size-dependent energy storage causes Kleiber’s law scaling of the metabolic rate in planarians

    Albert Thommen, Steffen Werner ... Jochen C Rink
    A combination of experimental and theoretical analysis identifies body size-dependent energy storage as the physiological cause of 3/4-power law scaling of the metabolic rate in planarians.
    1. Neuroscience
    2. Physics of Living Systems

    Scale-free behavioral dynamics directly linked with scale-free cortical dynamics

    Sabrina A Jones, Jacob H Barfield ... Woodrow L Shew
    Complex, multi-scale natural behaviors may arise from subpopulations of neurons in cerebral cortex operating near the tipping point of a phase transition, that is, near criticality.
    1. Neuroscience

    Using an achiasmic human visual system to quantify the relationship between the fMRI BOLD signal and neural response

    Pinglei Bao, Christopher J Purington, Bosco S Tjan
    The lower-level retinotopic visual cortex of humans born without the optic chiasm comprises two independent neuronal populations and forms a versatile model for quantifying the relationship between the fMRI BOLD signal and neural response.
    1. Physics of Living Systems
    2. Immunology and Inflammation

    Early life imprints the hierarchy of T cell clone sizes

    Mario U Gaimann, Maximilian Nguyen ... Andreas Mayer
    The rapid development of immune memory in infancy shapes the composition of T cell defenses throughout the human lifespan.
    1. Computational and Systems Biology
    2. Neuroscience

    Inferring multi-scale neural mechanisms with brain network modelling

    Michael Schirner, Anthony Randal McIntosh ... Petra Ritter
    Hybrid brain network models predict neurophysiological processes that link structural and functional empirical data across scales and modalities in order to better understand neural information processing and its relation to brain function.
    1. Neuroscience

    Internally generated time in the rodent hippocampus is logarithmically compressed

    Rui Cao, John H Bladon ... Marc W Howard
    Receptive fields for time in the hippocampus, like receptive fields for retinal space and receptive fields for numerosity, obey the Weber-Fechner law.
    1. Cell Biology

    Scaling of subcellular actin structures with cell length through decelerated growth

    Shane G McInally, Jane Kondev, Bruce L Goode
    The size of a subcellular structure, yeast actin cables, scales with the linear dimensions of the cell, which is achieved by feedback control of their growth rate.
    1. Genetics and Genomics

    A method for low-coverage single-gamete sequence analysis demonstrates adherence to Mendel’s first law across a large sample of human sperm

    Sara A Carioscia, Kathryn J Weaver ... Rajiv C McCoy
    A computational method and genome-wide scan of low-coverage single-cell sequencing data from a large sample of human sperm suggests balanced transmission of alleles to the gamete pool.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Large-scale analysis of the integration of enhancer-enhancer signals by promoters

    Miguel Martinez-Ara, Federico Comoglio, Bas van Steensel
    A high-throughput enhancer-enhancer-promoter reporter assay indicates that pairs of enhancers generally activate promoters in a near-additive manner, and that promoters transform their collective effect non-linearly.
    1. Evolutionary Biology
    2. Neuroscience

    Neuro-evolutionary evidence for a universal fractal primate brain shape

    Yujiang Wang, Karoline Leiberg ... Bruno Mota
    Cortices from 11 primate species share the same archetypal fractal shape, indicating a universal mechanism for primate and mammalian cortical folding, and suggesting novel shape biomarkers for brains.

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