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The first example of an animal where RNA-editing dramatically reshapes the entire proteome demonstrates that editing must be a critical evolutionary and adaptive force.

Combining CRISPR/Cas9 genome editing with gene drives may enable scientists to reversibly edit the genomes of diverse wild populations, an advance that could help eliminate diseases, support sustainable agriculture, and control invasive species.

High-throughput clonal tracking quantifies intrinsic differences between primary and secondary T cell response.

Find My Understudied Genes (FMUG) is a data-driven tool created to counteract the abandonment of understudied genes in -omics research.

An integrated framework for in vivo base edting allows to scalably validate candidate genes and DNA variants.

The three-dimensional architecture of the genome in distinct cell types predicts genes and regulatory elements involved in cell function and disease.

A novel computation tool for microbial community modeling predicts the evolution and diversification of E. coli in laboratory evolution experiments and gives insight into the underlying metabolic processes.

The emergent organization of bacterial proteomes—the integration of proteins into collective networks that encode function—can be defined purely from spectral analysis of ortholog covariation across extant diversity.

A highly efficient platform to engineer designer mutations in human stem cells using RNA-based delivery of prime editing components.

Bactabolize is a pipeline for rapid and scalable production of accurate bacterial strain-specific metabolic models and growth phenotype predictions.