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    1. Ecology
    2. Evolutionary Biology

    Reconstructing the phylogeny and evolutionary history of freshwater fishes (Nemacheilidae) across Eurasia since early Eocene

    Vendula Šlechtová, Tomáš Dvořák ... Jörg Bohlen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology

    Discovering Root Causal Genes with High Throughput Perturbations

    Eric V Strobl, Eric R Gamazon
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    The reuniens nucleus of the thalamus facilitates hippocampo-cortical dialogue during sleep

    Diellor Basha, Amirmohammad Azarmehri ... Igor Timofeev
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    • Solid
    1. Neuroscience

    Orexin population activity precisely reflects net body movement across behavioral and metabolic states

    Alexander L Tesmer, Paulius Viskaitis ... Denis Burdakov
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology

    Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in obesity

    Dan Wu, Venkateswararao Eeda ... Weidong Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    The Mycobacterium ulcerans toxin mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane to drive skin necrosis

    Louise Tzung-Harn Hsieh, Belinda S Hall ... Rachel E Simmonds
    The secreted toxin mycolactone has severe effects on the cells lining blood vessels that will play a critical role in the development of swelling in Buruli ulcer disease.
    1. Microbiology and Infectious Disease

    On the Role of VP3-PI3P Interaction in Birnavirus Endosomal Membrane Targeting

    Flavia A Zanetti, Ignacio Fernández ... Laura R Delgui
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Unraveling the impact of congenital deafness on individual brain organization

    Lénia Amaral, Wang Xiaosha ... Striem-Amit Ella
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner

    Xin Zhao, Yurim Chae ... Katherine Tschida
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Genetics and Genomics

    Intergenerational transport of double-stranded RNA in C. elegans can limit heritable epigenetic changes

    Nathan M Shugarts Devanapally, Aishwarya Sathya ... Antony M Jose
    Transport of double-stranded RNA from parental circulation to progeny using the transmembrane protein SID-1 can occur through multiple routes during C. elegans development and buffer heritable changes in gene expression.
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