New modelling, statistics, and experiments show that cellular populations of mitochondrial DNA (mtDNA) evolve during development according to solvable stochastic dynamics involving binomial partitioning and random turnover, facilitating a predictive and quantitative theory of the mtDNA bottleneck.
Mathematical modeling and data analysis show that, over evolutionary times, the yeast temporal program of replication strives to avoid stalling events and minimize interference between neighbor origins.
The spatial interactions between humans, large carnivores and herbivores cascade down in a complex but predictable way to lower trophic levels affecting regeneration of tree species in a temperate forest.
There is no relationship between the demographic susceptibility to extinction and the estimated extinction chronology among Sahul’s megafauna, suggesting that human choices, a species’ ecological requirements, and/or random climate variation instead determined the extinction chronology.
Computational modeling and molecular-biological analysis reveal the role of mechanical force and downstream Yap signaling in growth control during the development and regeneration of sensory epithelium of the inner ear.