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Human Biology and Medicine
Point of View: Predictive regulation and human design
Why does the human regulatory system, which evolution tuned for small satisfactions, now constantly demand 'more'?
A predictive focus of gain modulation encodes target trajectories in insect vision
Steven D Wiederman et al.
Visual neurons in the dragonfly predict the path of a moving target, even when it is occluded or crosses from one eye to the other.
Genetics and Genomics
Epigenetic age-predictor for mice based on three CpG sites
Yang Han et al.
Site-specific DNA methylation analysis at three CG dinucleotides by pyrosequencing provides a reliable measure for epigenetic aging of mice.
Midbrain dopamine neurons compute inferred and cached value prediction errors in a common framework
Brian F Sadacca et al.
Midbrain dopamine neurons in rats signal discrepancies between predicted and actual rewards, regardless of whether the rewards are predicted on the basis of experience or inference.
A prediction model of working memory across health and psychiatric disease using whole-brain functional connectivity
Masahiro Yamashita et al.
Human neuroimaging and machine learning reveals a generalizable relationship between brain connectivity and working memory ability across healthy populations and distinct psychiatric diagnoses.
Reward prediction error does not explain movement selectivity in DMS-projecting dopamine neurons
Rachel S Lee et al.
Despite the fundamental relationship between movement and value, they are represented in a separable manner in dopamine neurons.
Prediction error and repetition suppression have distinct effects on neural representations of visual information
Matthew F Tang et al.
Multivariate analyses of human electrophysiological recordings revealed that the brain represents unexpected visual stimuli with greater fidelity than expected stimuli which arose independently of simple habituation arising from repetition.
Large-scale replication study reveals a limit on probabilistic prediction in language comprehension
Mante S Nieuwland et al.
Large-scale replication study with brain potentials challenges the view that people routinely predict the phonological form of a predictable word during language comprehension.
YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis
Chuwen Lin et al.
The control of local cell properties such as epithelial cell number and mechanical force production by Hippo signaling is a major determinant of lung branching.
Computational and Systems Biology
Prediction of primary somatosensory neuron activity during active tactile exploration
Dario Campagner et al.
Primary trigeminal neurons encode rotational forces in awake mice as they explore an object with their whiskers, allowing accurate prediction of spiking during behaviour.
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