Prefrontal causal roles in bistable perception are dynamically changing and determined by the brain state to which the whole-brain activity pattern belongs.
A novel method of recording neural activity from the rodent medial prefrontal cortex reveals that the medial prefrontal cortex is composed of functionally distinct subregions that process economic decision information differentially along a dorso-ventral gradient.
Laura K Shanahan, Eva Gjorgieva ... Jay A Gottfried
Odor cues in sleep evoke content-specific signatures of neural reactivation in visual and prefrontal brain areas that predict subsequent memory performance in the wake state.
Prefrontal cortex plays a leading role in sequential decisions compared to posterior parietal cortex and relies on nonlinear integration of sensory and mnemonic information for decision formation.
Kristopher McEown, Yohko Takata ... Michael Lazarus
Loss of REM sleep increases sucrose and fat consumption in mice; and inhibiting the prefrontal cortex reverses the increased consumption of sucrose, but not fat, following REM sleep loss.
Targeting reductions in prefrontal PV interneuron activity and gamma power during cue presentation can rescue attention impairments in a mouse model of absence epilepsy.
Margaret M Cunniff, Eirene Markenscoff-Papadimitriou ... Vikaas Singh Sohal
In POGZ heterozygous mice, reduced anxiety-related avoidance is associated with decreased feedforward inhibition and theta synchrony in the hippocampal-prefrontal pathway.