358 results found
  1. Scientist and Parent: Planning during pregnancy

    Bridget M Kuehn
    Colleagues, funders and institutions can support pregnant researchers in a variety of ways.
    1. Cell Biology
    2. Human Biology and Medicine

    Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy

    Svasti Haricharan et al.
    The transcription factor STAT5 mediates the increased breast cancer risk associated with a late age pregnancy, but intermittent anti-STAT5 treatment can lower this risk and thus prevent breast cancer.
    1. Cell Biology
    2. Neuroscience

    Pregnancy-associated plasma protein-aa supports hair cell survival by regulating mitochondrial function

    Mroj Alassaf et al.
    Hair cell survival and mitochondrial function is supported by an extracellular stimulator of IGF1 signaling, the protease pregnancy-associated plasma protein-aa.
    1. Cell Biology
    2. Human Biology and Medicine

    Carcinogenesis: Targeting the link between late pregnancy and breast cancer

    Balabhadrapatruni VSK Chakravarthi, Sooryanarayana Varambally
    Insight
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    1. Cell Biology
    2. Developmental Biology

    Inverted formin 2 regulates intracellular trafficking, placentation, and pregnancy outcome

    Katherine Young Bezold Lamm et al.
    Loss of Inverted Formin-2 impairs intracellular trafficking and trophoblast invasion, resulting in maternal hypertension and intrauterine growth restriction, which represents a novel model of impaired placental invasion that encompasses critical aspects of the great obstetrical syndromes.
  2. Scientist and Parent: Looking for the best of both worlds

    Bridget M Kuehn
    Research institutions could do more to support scientists who are pregnant or have young children.
    1. Developmental Biology

    Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice

    Jorge López-Tello et al.
    Fetus and trophoblast interplay to regulate fetal nutrient supply and, ultimately, affect healthy growth.
    1. Computational and Systems Biology
    2. Human Biology and Medicine

    In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta

    Maria Pernemalm et al.
    Comprehensive mass spectrometry analysis of human plasma proteome reveals tissue leakage proteins, describes variability between individual plasma proteomes and demonstrates protein transfer across the placenta during pregnancy.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Epidemiological and ecological determinants of Zika virus transmission in an urban setting

    José Lourenço et al.
    An ento-epidemiological model reveals that what made the Zika virus a public health problem in Feira de Santana, Brazil, was a surprisingly high attack rate coupled with a low risk of Microcephaly per challenged pregnancy.
    1. Neuroscience

    Sex-dependent effects of in utero cannabinoid exposure on cortical function

    Anissa Bara et al.
    Adult male, but not female, rats showed altered neuronal function, inhibited synaptic plasticity and diminished social behavior following cannabinoid exposure during gestation in a model of cannabis use during pregnancy.

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