A female specifically expressed new protein-coding gene that has emerged out of non-coding sequences without detectable signatures of adaptive evolution affects female pregnancy cycles.

Accumulation of succinate during the in vitro modeling of embryonic stem cell state transition critically regulate cell fate.

The inhibitory or deletion effect of MELK does not impair the proliferation of basal-like breast cancer cell lines.

After DNA damage induction, transcription is blocked and XAB2 is released from R-loops allowing a subset of XAB2 molecules to interact with UV-stalled RNAP2 and participating to the TC-NER process.

Micropatterned differentiation of human ESCs generates gastrulation cell types – germ layers, extraembryonic, and primordial germ cells with primate characteristics – that show conserved sorting behaviors when dissociated and reseeded as single-cell mixture.

Mitochondrial metabolic fluxes display a subcellular spatial gradient within a single mouse oocyte, and the fluxes are not controlled by nutrient supply or energy demand of the cell, but by the intrinsic rates of mitochondrial respiration.

Biallelic MAD2L1BP variants contribute to oocyte metaphase I arrest in women with primary infertility and p31^comet is required for human oocyte maturation.