The use of preparatory activity in the smooth eye movement region of the frontal eye fields as a visual-motor gain signal allows preparation to progress without inappropriate movement.
Vamsi K Daliparthi, Ryosuke O Tachibana ... Todd F Roberts
Precisely sequenced patterns of neuronal activity associated with the production of a skilled behavior begin and end as part of orchestrated activity across functionally diverse populations of cortical premotor neurons.
John P Grogan, Matthias Raemaekers ... Sanjay G Manohar
Muscarinic antagonism is causally involved in motivation and incentivisation in healthy human participants, partially mediated via preparatory neural signatures, with implications for cholinergic treatment of Parkinson's disease.
Non-invasive disinhibition of the oculomotor system shows that ongoing preparatory activity in the superior colliculus has movement-generating potential and need not rise to threshold in order to produce a saccade.
Neuronal activity in the striatum keeps track of elapsed time during the time production task while that in the cerebellum correlates with stochastic variation of self-timing in the range of several hundreds of milliseconds.
Antonio H Lara, Gamaleldin F Elsayed ... Mark M Churchland
Voluntary movements are preceded by a temporally flexible preparatory neural process that is present regardless of whether movement is initiated rapidly or thoughtfully.
Michael A Gaffield, Britton A Sauerbrei, Jason M Christie
The activity of cerebellar Purkinje cells both represents and participates in organizing the temporal structure of a periodically performed motor action.
Low-dimensional external inputs are sufficient to control the speed of sequential activity, and to transition between persistent activity, in a network of neurons with both temporally symmetric and asymmetric learning.