217 results found
    1. Structural Biology and Molecular Biophysics

    A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery

    Zev A Ripstein et al.
    Understanding of bacterial protein degradation is illuminated by cryo-EM structures of the substrate-bound ClpXP complex from Neisseria meningitidis at 2.3 to 3.3 Å resolution.
  1. postits

    Innovation Sprint 2020: Design, test, learn, repeat

    We reflected on the first two iterations of the eLife Innovation Sprint, and are ready to share our plans for the next.
  2. eLife Latest: The costs of publishing

    Changes in annual expenses and publishing volume at eLife show it is possible to run a selective journal with a mid-range publication fee.
    1. Neuroscience

    Identification of slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour

    Judit García-González et al.
    Zebrafish studies are able to predict loci and biological pathways affecting human behaviour, paving the way to better understanding of the biological underpinnings of psychiatric disease.
  3. Peer Review: Publishing in the time of COVID-19

    Michael B Eisen et al.
    eLife is making changes to its policies on peer review in response to the impact of COVID-19 on the scientific community.
    Editorial
    Available as:
    • HTML
    • PDF
  4. eLife Ambassadors: Contributions start to bear fruit

    Outputs from the eLife Ambassadors programme are beginning to emerge from projects on a wide range of topics – from reproducibility and peer review to mentoring and leadership.
  5. eLife and COVID-19: Our response to the pandemic

    eLife’s editors, early-career advisors and executive staff are working to support researchers affected by the ongoing coronavirus outbreak.
  6. eLife and COVID-19: Keeping communications open with online research talks

    eLife hosts online seminars to support early-career researchers to present their research online instead of in person.
  7. Webinar Report: Everything you need to know about Research Resource Identifiers

    In this recent webinar, Anita Bandrowski from the Resource Identification Initiative discusses a relatively easy way to improve the reproducibility of your research.
    1. Developmental Biology

    Ordered patterning of the sensory system is susceptible to stochastic features of gene expression

    Ritika Giri et al.
    How gene expression noise is regulated is critical for cell fate and tissue patterning.

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