113 results found
    1. Developmental Biology

    Specification of diverse cell types during early neurogenesis of the mouse cerebellum

    John W Wizeman et al.
    Single-cell RNA sequencing resolves inter- and intra-population heterogeneity, identifies rare cell types, and reconstructs specification trajectories during early neurogenesis of the mouse cerebellum.
  1. eLife Latest: How publishers are coming on board with open annotations

    We explore how publishers are adopting the newly customised Hypothesis annotation platform to promote scientific discussion online.
  2. In Europe: eLife contributes to a report on the future of scholarly communication

    An Expert Group appointed by the European Commission identifies reform of the scholarly incentive system as a key requirement for the continuing improvement of research communication.
  3. Webinar Report: Graphic design tips for creating effective figures

    Learn how you can improve how you communicate your science visually.
    1. Genetics and Genomics

    Molecular safeguarding of CRISPR gene drive experiments

    Jackson Champer et al.
    Genes drives utilizing synthetic target sites and the split-Cas9 system have similar performance to standard drives.
  4. Scientific Publishing: Progress and promise

    Randy Schekman
    As he prepares to step down as the Editor-in-Chief of eLife, Randy Schekman reflects on the origins of the journal, the eLife approach to peer review, and current challenges in scientific publishing.
    Editorial
    Available as:
    • HTML
    • PDF
    1. Developmental Biology
    2. Plant Biology

    Quantitative analysis of auxin sensing in leaf primordia argues against proposed role in regulating leaf dorsoventrality

    Neha Bhatia et al.
    Top-bottom patterning of leaves is not specified by an asymmetry in the distribution of the plant hormone auxin, in contrast to a previous proposal.
  5. Peer Review: First results from a trial at eLife

    New approach to peer review proves popular with authors, with very similar acceptance rates for male and female last authors, but with higher acceptance rates for late-career researchers compared to their early- and mid-career colleagues.
    1. Evolutionary Biology

    Evolution of cation binding in the active sites of P-loop nucleoside triphosphatases in relation to the basic catalytic mechanism

    Daria N Shalaeva et al.
    In potassium-dependent NTPases, insertion of the activating potassium ion into the active site leads to rotation of the gamma-phosphate yielding a near-eclipsed, catalytically productive conformation of the triphosphate chain.
  6. Meeting Report: Changing the culture of scholarly communication

    eLife board member Dr. Prachee Avasthi led a lively evening debate in Cambridge, UK.

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