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Electrophysiological and optical analysis of neurotransmitter release at central synapses reveals that glutamate signalling is not required for the long-term potentiation (LTP) of presynaptic function, and instead only promotes presynaptic long-term depression (LTD).

Glutamatergic projections from basolateral to central amygdala, implicated in neuropsychiatric disorders, develop rapidly during early postnatal period and their development is modulated via endogenously active kainate receptors.

Elimination of GABA_A receptors from the axon terminals of specific retinal bipolar cell types alters the sensitivity and kinetics of retinal output.

Young neurons of the adult hippocampus are synaptically activated by a small group of non-overlapping afferent excitatory fibers, due to high synaptic gain and sparse connectivity, important for sparse and orthogonal coding during hippocampal information processing.

In a population of mammalian central synapses, spontaneous and evoked neurotransmitter release processes are independently distributed; yet, postsynaptic receptors within a single synapse preferentially receive neurotransmitter from only one mode of release.

Associative plasticity of proximal and distal granule cell inputs to Purkinje cells enables time dependent association of information from local and distant receptive fields.

Genetic analysis of Ntn1 in adult mouse midbrain neurons reveals its function in maintaining excitatory synapses, loss of Ntn1 function in inhibitory neurons is significantly detrimental to mesolimbic system function.

Dimensionality reduction techniques reveal how the organization of neurotransmitter receptor and transporter co-expression in the human brain may bridge the gap between brain structure and function.

Molecular engineering can generate light-sensitive NMDA receptors with specific subunit combinations.

Experiments examining the actions of morphine on single neurons from one of the brain's reward centers, the VTA, reveal the mechanism by which the drug exerts its hedonic effects.