120 results found
    1. Neuroscience

    LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses

    Alessandra Sclip, Thomas C Südhof
    LAR-RPTPs are not essential for synapse formation, but they are important determinants of synapse properties as they contribute to regulate postsynaptic NMDA receptor function.
    1. Developmental Biology
    2. Neuroscience

    The laminar organization of the Drosophila ellipsoid body is semaphorin-dependent and prevents the formation of ectopic synaptic connections

    Xiaojun Xie et al.
    The organization of layered/laminated axon projections in specific regions of the fruitfly central brain is regulated by short-range repulsive guidance and is critical for local inhibitory circuit formation and function.
    1. Neuroscience

    Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans

    Xi Chen et al.
    Plexin controls the spatial distribution of synapses by locally inhibiting Rap2 small GTPase activity along the axon, and a Rap2 effector, TNIK, which also plays a key role in inhibiting synapse number.
    1. Developmental Biology
    2. Neuroscience

    Directional selectivity of afferent neurons in zebrafish neuromasts is regulated by Emx2 in presynaptic hair cells

    Young Rae Ji et al.
    Emx2 mediates the directional selectivity of neuromasts by regulating hair bundle orientation in hair cells, and by selecting afferent neuronal targets.
    1. Neuroscience

    CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory

    Miou Zhou et al.
    Repression of the G protein-coupled chemokine receptor CCR5 enhances MAPK/CREB signaling, long-term potentiation, somatosensory cortical plasticity, and learning and memory, while CCR5 over-activation by viral proteins may contribute to HIV-associated cognitive deficits.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Proteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels

    Ivan Kadurin et al.
    Multiple roles of the auxiliary calcium channel α2δ subunits require proteolytic cleavage of the precursor protein into α2 and δ.
    1. Developmental Biology

    Antagonistic regulation by insulin-like peptide and activin ensures the elaboration of appropriate dendritic field sizes of amacrine neurons

    Jiangnan Luo et al.
    Afferent-derived factors control the elaboration of appropriate and robust sizes of dendritic arbors by dynamically modulating dendritic growth parameters.
    1. Neuroscience

    Interactions between Dpr11 and DIP-γ control selection of amacrine neurons in Drosophila color vision circuits

    Kaushiki P Menon et al.
    The survival of Drosophila amacrine neurons is controlled by neurotrophic signaling mediated by interactions between the cell surface protein DIP-γ and its partner Dpr11, which is expressed on presynaptic photoreceptors.
    1. Developmental Biology
    2. Neuroscience

    Synapse maintenance is impacted by ATAT-2 tubulin acetyltransferase activity and the RPM-1 signaling hub

    Melissa A Borgen et al.
    Genetic, developmental and pharmacological analysis in Caenorhabditis elegans demonstrate that ATAT-2 tubulin acetyltransferase activity regulates synapse maintenance by acting within the RPM-1 signaling network, but independent of the DLK-1 MAP3K.
    1. Neuroscience

    A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites

    Nan Jiang et al.
    Epidermal cells in vertebrates and invertebrates ensheath portions of somatosensory neurons via a conserved morphogenetic mechanism, and this ensheathment regulates morphogenesis and function of Drosophila nociceptive neurons.

Refine your results by:

Type
Research categories