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    1. Computational and Systems Biology

    Discovering Root Causal Genes with High Throughput Perturbations

    Eric V Strobl, Eric R Gamazon
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Quantifying microbial fitness in high-throughput experiments

    Justus Wilhelm Fink, Michael Manhart
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Electrostatics of Salt-Dependent Reentrant Phase Behaviors Highlights Diverse Roles of ATP in Biomolecular Condensates

    Yi-Hsuan Lin, Tae Hun Kim ... Hue Sun Chan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation

    James B Isbister, András Ecker ... Michael W Reimann
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

    Juliet R Girard, Lauren M Goins ... Utpal Banerjee
    A combination of mRNA sequencing and genetic analysis reveals mechanisms that govern the development of distinct differentiated blood cell types from hematopoietic progenitors.
    1. Cell Biology
    2. Cancer Biology

    Cell crowding induces TRPV4 inhibition and its relocation to plasma membranes, implicating pro-invasive cell volume reduction mechanotransduction pathway

    Xiangning Bu, Nathanael Ashby ... Inhee Chung
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Ultrastructural sublaminar-specific diversity of excitatory synaptic boutons in layer 1 of the adult human temporal lobe neocortex

    Astrid Rollenhagen, Akram Sadeghi ... Joachim HR Lübke
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    • Incomplete
    1. Neuroscience

    High-Resolution Laminar Identification in Macaque Primary Visual Cortex Using Neuropixels Probes

    Li A Zhang, Peichao Li, Edward M Callaway
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Multiplexed Assays of Human Disease-relevant Mutations Reveal UTR Dinucleotide Composition as a Major Determinant of RNA Stability

    Jia-Ying Su, Yun-Lin Wang ... Chien-Ling Lin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis

    Vivian Salgueiro, Jorge Bertol ... Rafael Prados-Rosales
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
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