A novel compartment model identifies the impact of malaria strain diversity on biogeographic drug resistance patterns, supported by empirical evidence.
Shifting from girls-only to gender-neutral HPV vaccination strategy improves the resilience of cervical cancer prevention and enhances progress towards cervical cancer elimination.
Oliver John Watson, Robert Verity ... Hannah C Slater
The timing of surveillance for pfhrp2/3-deletions within a transmission season impacts estimates of the proportion of false-negative RDTs due to deletions, which may cause premature decisions to change RDT.
The optimal allocation strategy prioritizes funding to high-transmission settings in sub-Saharan Africa, but highlights a trade-off between reducing clinical malaria burden and reducing the global population at risk of malaria.
Lawrence Lubyayi, Harriet Mpairwe ... Alison M Elliott
In a Ugandan birth cohort, early childhood infection-exposure, notably to malaria, helminths, and diarrhoea, is associated with lower prevalence of atopy and allergy-related diseases in later childhood.
In metastatic NSCLC patients, CHIP showed minimal impact on immunotherapy response but was more prevalent and associated with inflammatory pathways in myeloid cells, particularly in lung squamous cell carcinoma.
Diminished incidence of COVID-19 amongst healthcare workers in a comprehensive screening programme demonstrates how effective infection control measures and staff testing can prevent hospitals becoming independent 'hubs' of SARS-CoV-2 transmission.
