Clive P Morgan, Jocelyn F Krey ... Peter G Barr-Gillespie
A new purification method for stereocilia membranes enables efficient immunoaffinity purification of rare protein complexes from hair cell stereocilia, including the newly described complex of deafness genes PDZD7 and MYO7A.
Smrithi Prem, Bharati Dev ... Emanuel DiCicco-Bloom
Alterations in mTOR signaling drive similar dysregulations in the critical mid-fetal neurodevelopmental processes of neurite outgrowth and cell migration in two distinct subsets of autism, idiopathic and 16p11.2 deletion.
Echolocating toothed whales can detect and react to sudden prey movements during close approaches with speeds similar to ultra-fast tracking responses in human vision.
Digital reconstruction of environment combined with eye and head-tracking enabled the process of prey-detection and capture to be seen from the freely moving mouse’s point-of-view and shows the exact visual-field and retinal location mice use when chasing prey and the advantage.
Jolle Wolter Jolles, Matthew MG Sosna ... Iain D Couzin
Detailed tracking of live predators attacking live schools of prey reveals the crucial interplay between predator attack strategy and prey behaviour and positioning in determining the predation risk within mobile animal groups.
Laura Stidsholt, Antoniya Hubancheva ... Peter T Madsen
Greater mouse-eared bats prefer to hunt large ground insects despite high failure rates, but switch to smaller, easily caught flying insects in response to environmental changes.
A computational model, based on single-cell features like contractility and polarizability, quantitatively describes cellular dynamics from the single cell level up to small cohorts and confluent tissues.