167 results found
    1. Developmental Biology

    Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution

    Julie Uveira, Antoine Donati ... Tsuyoshi Momose
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Developmental Biology

    Comprehensive profiling of migratory primordial germ cells reveals niche-specific differences in non-canonical Wnt and Nodal-Lefty signaling in anterior vs posterior migrants

    Rebecca G Jaszczak, Jay W Zussman ... Diana J Laird
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Atlas of Fshr expression from novel reporter mice

    Hongqian Chen, Hui-Qing Fang ... Peng Liu
    Exploiting the power of the Fshr reporter, the first comprehensive genetic record of the spatial distribution of FSHR expression offers prospects for extensive exploration of FSH-FSHR biology.
    1. Genetics and Genomics

    Intergenerational transport of double-stranded RNA in C. elegans can limit heritable epigenetic changes

    Nathan Shugarts, Aishwarya Sathya ... Antony M Jose
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    Caspar specifies primordial germ cell count and identity in Drosophila melanogaster

    Subhradip Das, Sushmitha Hegde ... Girish S Ratnaparkhi
    During Drosophila primordial germ cells (PGCs) specification, the centrosome and germplasm are subject to regulation, during the maternal zygotic transition, by Caspar/TER94-dependent degradative pathways that influence PGC determinants.
    1. Cell Biology
    2. Developmental Biology

    Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis

    Azali Azlan, Li Zhu, Ryuya Fukunaga
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Endogenous FGFs drive ERK-dependent cell fate patterning in 2D human gastruloids

    Kyoung Jo, Zong-Yuan Liu ... Idse Heemskerk
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology

    Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

    Ewa K Bomba-Warczak, Karen M Velez ... Francesca E Duncan
    Exceptionally long-lived macromolecules in mammalian ovaries and oocytes serve as pillars for lifelong reproductive health span.
    Version of Record
    Short Report
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    Nuclear Argonaute protein NRDE-3 switches small RNA binding partners during embryogenesis coincident with the formation of SIMR granules

    Shihui Chen, Carolyn M Phillips
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Evolutionary Biology
    2. Medicine

    The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis

    Rion Brattig-Correia, Joana M Almeida ... Paulo Navarro-Costa
    An interdisciplinary research platform reveals that the transcriptional identity of metazoan male germ cells is built around a small network of deeply conserved gene interactions with an overarching functional impact.
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