3,411 results found
    1. Neuroscience

    Perisomatic GABAergic synapses of basket cells effectively control principal neuron activity in amygdala networks

    Judit M Veres et al.
    Basket cells expressing parvalbumin or cholecystokinin provide equally effective control of principal neuron activity via their perisomatic synapses in the basal amygdala.
    1. Developmental Biology

    An abundant quiescent stem cell population in Drosophila Malpighian tubules protects principal cells from kidney stones

    Chenhui Wang, Allan C Spradling
    Drosophila renal stem cells are exceptional in abundance, require induction to produce a single cell type, principal cells, and mitigate damage during adulthood associated with external stresses.
    1. Neuroscience

    Extracting grid cell characteristics from place cell inputs using non-negative principal component analysis

    Yedidyah Dordek et al.
    Computational modeling of the brain’s navigation system reveals that place cells can drive the formation of hexagonal patterns experimentally observed in grid cells activity.
    1. Neuroscience

    Principal cells of the brainstem’s interaural sound level detector are temporal differentiators rather than integrators

    Tom P Franken et al.
    Principal neurons of the brainstem nucleus comparing sound level at the two ears do not have the slow response properties previously attributed to them, but are instead specialized for fast weighing of excitation and inhibition.
    1. Microbiology and Infectious Disease

    MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis

    Saman Hussain et al.
    MreB filaments bind, orient, and move along the direction of greatest membrane curvature, thus orienting the insertion of new glycan strands around the cell circumference in a manner that may help establish and maintain rod shape.
    1. Neuroscience

    A principle of economy predicts the functional architecture of grid cells

    Xue-Xin Wei et al.
    Mathematical modeling suggests that grid cells in the rodent brain use fundamental principles of number theory to maximize the efficiency of spatial mapping, enabling animals to accurately encode their location with as few neurons as possible.
    1. Cell Biology
    2. Developmental Biology

    Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts

    Max Werth et al.
    A combination of genetic and molecular assays revealed that transcription factor Tfcp2l1 provides the basis for cell patterning and physiologic coordination in kidney collecting ducts.
    1. Neuroscience

    Hipposeq: a comprehensive RNA-seq database of gene expression in hippocampal principal neurons

    Mark S Cembrowski et al.
    Gene expression was analyzed in hippocampal principal cells, enabling cellular phenotyping and revealing novel organizational principles; complementing this, a publicly available website is released to provide outside analysis and visualization of hippocampal RNA-seq data in an accessible fashion.
  1. Meta-Research: Journal policies and editors’ opinions on peer review

    Daniel G Hamilton et al.
    A survey of journals and editors in five areas of research - ecology, economics, medicine, physics and psychology - reveals a range of differences in their approach to peer review.

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