1,792 results found
    1. Neuroscience

    Parallel processing by distinct classes of principal neurons in the olfactory cortex

    Shivathmihai Nagappan, Kevin M Franks
    In vivo recordings from identified cell classes in the olfactory cortex of a novel transgenic mouse reveal that distinct classes of principal neurons operate largely in parallel and differentially process odor information.
    1. Cell Biology
    2. Neuroscience

    An alternative splicing switch shapes neurexin repertoires in principal neurons versus interneurons in the mouse hippocampus

    Thi-Minh Nguyen, Dietmar Schreiner ... Peter Scheiffele
    Interneuron-specific alternative splice variants of the synaptic receptor neurexin are critical for hippocampal network activity and short-term memory.
    1. Neuroscience

    Perisomatic GABAergic synapses of basket cells effectively control principal neuron activity in amygdala networks

    Judit M Veres, Gergő A Nagy, Norbert Hájos
    Basket cells expressing parvalbumin or cholecystokinin provide equally effective control of principal neuron activity via their perisomatic synapses in the basal amygdala.
    1. Neuroscience

    A novel class of inferior colliculus principal neurons labeled in vasoactive intestinal peptide-Cre mice

    David Goyer, Marina A Silveira ... Michael T Roberts
    VIP neurons are a novel class of inferior colliculus stellate neurons that project to long-range auditory and non-auditory targets and integrate inputs from the auditory brainstem and contralateral IC.
    1. Neuroscience

    Cell-specific gain modulation by synaptically released zinc in cortical circuits of audition

    Charles T Anderson, Manoj Kumar ... Thanos Tzounopoulos
    Synaptic zinc is a novel modulator of cortical sound processing - a modulator that increases the gain of principal neurons, but reduces the gain of interneurons.
    1. Neuroscience

    Rhythmic coordination of hippocampal neurons during associative memory processing

    Lara M Rangel, Jon W Rueckemann ... Howard Eichenbaum
    Different rhythms uniquely contribute to task-related processing in the hippocampus, and changes in the rhythmic profile of the hippocampus reflect dynamic coordination of its cell activity.
    1. Neuroscience

    Hipposeq: a comprehensive RNA-seq database of gene expression in hippocampal principal neurons

    Mark S Cembrowski, Lihua Wang ... Nelson Spruston
    Gene expression was analyzed in hippocampal principal cells, enabling cellular phenotyping and revealing novel organizational principles; complementing this, a publicly available website is released to provide outside analysis and visualization of hippocampal RNA-seq data in an accessible fashion.
    1. Neuroscience

    Thalamus and claustrum control parallel layer 1 circuits in retrosplenial cortex

    Ellen KW Brennan, Izabela Jedrasiak-Cape ... Omar J Ahmed
    Parallel input streams to layer 1 identify a computationally distinct principal neuronal subtype ideally positioned to support spatial orientation computations in the granular retrosplenial cortex.
    1. Neuroscience

    Principal cells of the brainstem’s interaural sound level detector are temporal differentiators rather than integrators

    Tom P Franken, Philip X Joris, Philip H Smith
    Principal neurons of the brainstem nucleus comparing sound level at the two ears do not have the slow response properties previously attributed to them, but are instead specialized for fast weighing of excitation and inhibition.
    1. Neuroscience

    Non-linear developmental trajectory of electrical phenotype in rat substantia nigra pars compacta dopaminergic neurons

    Martial A Dufour, Adele Woodhouse ... Jean-Marc Goaillard
    The development of the electrical phenotype of neurons can be precisely quantified and dissected using a combination of multi-variate statistical analyses and a systematic electrophysiological characterization of electrical properties.

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