466 results found
  1. Point of View: Priority of discovery in the life sciences

    Ronald D Vale, Anthony A Hyman
    Disclosing work prior to submission to a journal would benefit scientists seeking to be acknowledged for their discoveries.
    1. Cell Biology
    2. Computational and Systems Biology

    Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation

    John M Ankers et al.
    Cell imaging and mathematical modelling show reciprocal cross-regulation between inflammatory signalling and cell cycle timing, which is mediated through functional interactions between NF-B and E2F proteins.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Point of View: Is cell size a spandrel?

    Ariel Amir
    Analysis of experiments on bacteria suggests that the dependence of cell size on growth rate is not an adaptation but a causal consequence of a regulatory mechanism that controls DNA replication.
    1. Neuroscience

    Serial Behaviour: What can fruit flies teach us about karate?

    Helen H Yang, Thomas R Clandinin
    Insight
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    1. Microbiology and Infectious Disease

    Point of View: What next for gain-of-function research in Europe?

    Robin Fears, Volker ter Meulen
    A EASAC working group on gain-of-function research has emphasised the importance of ensuring that the necessary safeguards and policies are in place.
    1. Developmental Biology and Stem Cells

    Addressing the ethical issues raised by synthetic human entities with embryo-like features

    John Aach et al.
    Guidelines governing research into embryos need to be updated in a way that reflects the moral status of synthetic human entities generated using the methods of synthetic biology.
  2. Point of View: How should novelty be valued in science?

    Barak A Cohen
    An over-emphasis on novelty is having detrimental effects on science.
  3. Research: Decoupling of the minority PhD talent pool and assistant professor hiring in medical school basic science departments in the US

    Kenneth D Gibbs Jr et al.
    A systems-level analysis of the biomedical workforce in the US shows that current strategies to enhance faculty diversity are unlikely to have a significant impact, and that there is a need to increase the number of PhDs from underrepresented minority backgrounds who move on to postdoctoral positions.
  4. Living Science: Triaging Shakespeare

    Indira M Raman
    What if every creative endeavor had to go through Peer Review? Indira M Rama considers the possibility.

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