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    1. Neuroscience

    A neuronal least-action principle for real-time learning in cortical circuits

    Walter Senn, Dominik Dold ... Mihai A Petrovici
    A principle from which the neuronal dynamics and synaptic plasticity in arbitrary network architectures can be inferred, so that output errors are online minimized while simultaneously processing sensory input streams.
    1. Neuroscience

    Single neurons and networks in the claustrum integrate input from widespread cortical sources

    Andrew M Shelton, David K Oliver ... Adam M Packer
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Neural Correlates and Reinstatement of Recent and Remote Memory: A Comparison Between Children and Young Adults

    Iryna Schommartz, Philip F Lembcke ... Yee Lee Shing
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    The emergence and evolution of gene expression in genome regions replete with regulatory motifs

    Timothy Fuqua, Yiqiao Sun, Andreas Wagner
    Mutagenizing sequences enriched with promoter motifs creates gene expression de novo, and helps to understand promoter logic, regulatory evolution, and the birth of de novo genes.
    1. Neuroscience

    Body size as a metric for the affordable world

    Xinran Feng, Shan Xu ... Jia Liu
    The human body shapes how we perceive and interact with the environment, with body size serving as a boundary for defining potential actions, hereby enlightening research on foundation agents.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into actin isoforms

    Amandeep S Arora, Hsiang-Ling Huang ... Krishna Chinthalapudi
    The functional differences between actin isoforms have been explored through structural studies.
    1. Neuroscience

    Specific lexico-semantic predictions are associated with unique spatial and temporal patterns of neural activity

    Lin Wang, Gina Kuperberg, Ole Jensen
    The prediction of specific words is associated with distinct spatial and temporal patterns of neural activity within the left inferior and medial temporal regions before the predicted word is presented.
    1. Neuroscience

    Functional brain reconfiguration during sustained pain

    Jae-Joong Lee, Sungwoo Lee ... Choong-Wan Woo
    Human neuroimaging with time-evolving network analysis reveals dynamic interactions among multiple functional brain networks in response to sustained pain.
    1. Computational and Systems Biology

    Homeostasis, injury, and recovery dynamics at multiple scales in a self-organizing mouse intestinal crypt

    Louis Gall, Carrie Duckworth ... Carmen Pin
    Novel modelling strategies can integrate the dynamics of processes regulating the intestinal epithelium at multiple scales in homeostasis and following perturbations to provide unprecedented insights into the biology of the epithelium and support the development of safer novel drug candidates.
    1. Developmental Biology
    2. Physics of Living Systems

    The geometric basis of epithelial convergent extension

    Fridtjof Brauns, Nikolas H Claussen ... Boris I Shraiman
    Active and passive contributions to cell shape change and rearrangements can be distinguished from observed cell geometry, revealing the self-organization mechanisms underlying internally-driven epithelial convergent extension.