649 results found
  1. Research: Decoupling of the minority PhD talent pool and assistant professor hiring in medical school basic science departments in the US

    Kenneth D Gibbs Jr et al.
    A systems-level analysis of the biomedical workforce in the US shows that current strategies to enhance faculty diversity are unlikely to have a significant impact, and that there is a need to increase the number of PhDs from underrepresented minority backgrounds who move on to postdoctoral positions.
  2. Mental Health in Academia: What about faculty?

    Hilal A Lashuel
    After two heart attacks in three years, an associate professor discusses the challenges of faculty life.
    1. Neuroscience

    Diminished responses to bodily threat and blunted interoception in suicide attempters

    Danielle C DeVille et al.
    People who have attempted suicide exhibit blunted sensory processing during breathing and pain perturbations, as well as lower heartbeat perception accuracy and reduced mid/posterior insula activity during interoceptive attention.
    1. Structural Biology and Molecular Biophysics

    Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

    Dari Kimanius et al.
    Using GPUs for the costly computations in cryo-EM enables structure determination in mere days on a single workstation.
  3. Point of View: The sustainable professor

    Elizabeth S Haswell
    Responsible agricultural practices provide a useful lens through which to consider the lives and careers of researchers.
    1. Cancer Biology
    2. Cell Biology

    Tracking cells in epithelial acini by light sheet microscopy reveals proximity effects in breast cancer initiation

    Ashna Alladin et al.
    The presented primary epithelial acinus-based platform for studying interactions between normal and malignant cells will enable in depth analysis of the tumor initiation process on a molecular level.
  4. Meta-Research: Gender variations in citation distributions in medicine are very small and due to self-citation and journal prestige

    Jens Peter Andersen et al.
    In studies of gender disparities in academia, increased focus is required on within-group variability and between-group overlap of distributions when interpreting and reporting results.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Generation of inner ear hair cells by direct lineage conversion of primary somatic cells

    Louise Menendez et al.
    Direct reprogramming of somatic cells to an inner ear sensory hair cell-like state provides an experimental platform to identify causes and treatments for hair cell loss and hearing deficits.
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals

    Shogo Sawaguchi et al.
    The transfer of O-GlcNAc by EOGT to specific EGF repeats of NOTCH1 promotes DLL4 binding, Notch signaling, and retinal vascular development.
    1. Neuroscience

    Microsecond interaural time difference discrimination restored by cochlear implants after neonatal deafness

    Nicole Rosskothen-Kuhl et al.
    Early deaf human CI users are often insensitive to sub-millisecond interaural time differences (ITDs); however, with synchronized CIs, early deafened rats learned to lateralize small ITDs near 50 µs.

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