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    1. Developmental Biology and Stem Cells
    2. Neuroscience

    Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling

    Sung-Ho Huh et al.
    Otic epithelial Fibroblast Growth Factors control the number of cochlear sensory progenitor cells through an FGF responsive periotic mesenchyme.
    1. Cell Biology
    2. Neuroscience

    Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing

    Piergiorgio La Rosa et al.
    The RNA binding protein Sam68 links a key metabolic route to the neural stem cell fate in the developing mouse brain.
    1. Neuroscience

    The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice

    Xiang-Chun Ju et al.
    Introducing a hominoid-specific gene into mice induces cortical folding.
    1. Developmental Biology and Stem Cells

    Paracrine Met signaling triggers epithelial–mesenchymal transition in mammary luminal progenitors, affecting their fate

    Amandine Di-Cicco et al.
    Mammary progenitors identified by a new marker, ICAM-1, undergo epithelial-mesenchymal transition and luminal-to-basal switch in response to paracrine Met activation.
    1. Developmental Biology and Stem Cells

    ErbB expressing Schwann cells control lateral line progenitor cells via non-cell-autonomous regulation of Wnt/β-catenin

    Mark E Lush, Tatjana Piotrowski
    Schwann cell induced quiescence of mechanosensory progenitor cells is mediated by inhibition of Wnt/β-catenin signaling.
    1. Developmental Biology and Stem Cells

    Pvr expression regulators in equilibrium signal control and maintenance of Drosophila blood progenitors

    Bama Charan Mondal et al.
    The THAP-domain protein Bip1, along with other proteins Nup98 and RpS8, controls the expression of the protein Pvr, a critical non-cell-autonomous regulator of Drosophila blood progenitor maintenance.
    1. Developmental Biology and Stem Cells

    Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development

    Shahram Jevin Poureetezadi et al.
    Prostaglandin synthesis and PGE2 receptor activity are essential for mediating segmentation of renal progenitors during pronephros formation in the zebrafish.
    1. Cancer Biology
    2. Developmental Biology and Stem Cells

    Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations

    Shaina N Porter et al.
    Age-specific transcriptional responses to Flt3-ITD and cooperating Flt3/Runx1 mutations cause hematopoietic stem cell depletion and myeloid progenitor expansion during adult, but not fetal/neonatal, stages of development.
    1. Cell Biology
    2. Neuroscience

    Proneurotrophin-3 promotes cell cycle withdrawal of developing cerebellar granule cell progenitors via the p75 neurotrophin receptor

    Juan Pablo Zanin et al.
    The p75 neurotrophin receptor regulates when granule neuron progenitors exit the cell cycle in the developing cerebellum.
    1. Developmental Biology and Stem Cells

    Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration

    Nicole D Paris et al.
    Ablation of canonical TGFβ signaling in muscle stem cells at any age is detrimental, and not beneficial, to effective skeletal muscle regeneration due to the promotion of premature fate commitment at the expense of progenitor amplification.