Pcdhg determine survival of the GABAergic cortical interneuron population that is necessary to establish and maintain proper excitatory to inhibitory balance in the cerebral cortex.

Mitochondrial quality control in the germline is mediated by regulators of both programmed cell death and the aging program.

Autophagy is critical for the turnover of inflammatory signaling complexes containing RHIM-domain proteins.

Programmed cell death during plant development (dPCD) is crucial for Arabidopsis thaliana root defense, limiting microbial invasion and maintaining a balanced relationship with beneficial microbes.

A cryo-electron microscopy model of the active human apoptosome illuminates how this "wheel of death" binds the protease procaspase-9 to initiate programmed cell death.

Developmental cell death plays a key role during insect neurogenesis and is increased in specific neuronal populations in flies that have evolved flightlessness.

Extrinsic signals establish an invariant and stereotyped pattern of neuronal differentiation and programmed cell death in the Drosophila visual system.

Physical and chemical interactions with bacteria influence the life and death of Emiliania huxleyi, a bloom-forming micro-alga important in global biogeochemical cycles.

Genetic and microscopy analyses identify a programmed cell death mechanism that kills a cell subpopulation in a bacterial biofilm where oxygen is limiting, thereby promoting dispersion of newborn motile cells through the action of DNA released by dead cells.

Estrogen aggravates mammary involution through lysosome-mediated cell death, neutrophil recruitment via CXCR2 signalling, neutrophil-mediated inflammation and adipocyte repopulation.