678 results found
    1. Neuroscience

    Sensory experience controls dendritic structure and behavior by distinct pathways involving degenerins

    Sharon Inberg, Yael Iosilevskii ... Benjamin Podbilewicz
    Mechanosensory isolation of C. elegans nematodes independently induces homeostatic structural changes in the dendritic tree and differential response to mechanical stimulation, both these structural and behavioral outcomes are mediated by degenerins and do not affect presynaptic calcium dynamics.
    1. Cancer Biology

    Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric cancer

    Yue Zhang, Hanbing Wang ... Jia Wei
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Cell Biology
    2. Neuroscience

    Zebrafish live imaging reveals only around 2% rather than 50% of motor neurons die through apoptosis during early development

    Hao Jia, Hongmei Yang, Kathy Qian Luo
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    • Inadequate
    1. Cancer Biology
    2. Computational and Systems Biology

    Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility

    Rosalyn W Sayaman, Masaru Miyano ... Mark A LaBarge
    Breast luminal epithelial cells are the hotspots of aging-associated changes, which prime aged epithelia for oncogenic gene activation and may explain individual differences in breast cancer susceptibility due to the aging-associated increase in gene expression variances in luminal epithelia.
    1. Immunology and Inflammation

    The protective roles of eugenol on type 1 diabetes mellitus through NRF2-mediated oxidative stress pathway

    Yalan Jiang, Pingping He ... Xiaoou Shan
    Eugenol has the ability to improve the type 1 diabetes mellitus through NRF2-mediated oxidative stress pathway.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

    Liza Dahal, Thomas GW Graham ... Xavier Darzacq
    Type II nuclear receptors do not always compete for a limiting pool of their obligate partner RXRa.
    1. Neuroscience

    Control of innate olfactory valence by segregated cortical amygdala circuits

    James R Howe, Chung-Lung Chan ... Cory M Root
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology
    2. Neuroscience

    Identification of neurodevelopmental organization of the cell populations of juvenile Huntington’s disease using dorso-ventral HD organoids and HD mouse embryos

    Karolina Świtońska-Kurkowska, Jakub Kubiś ... Maciej Figiel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Immunology and Inflammation

    The Human Mitochondrial Genome Encodes for an Interferon-Responsive Host Defense Peptide

    Michelle C Rice, Maria Imun ... Changhan Lee
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid

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