Browse the search results

In neocortex, Nav1.1 is expressed in neocortical pyramidal tract projection neurons and a minor subpopulation of cortico-cortical projection neurons in addition to its predominant expression in inhibitory neurons, while the majority of cortico-thalamic, cortico-striatal, and cortico-cortical neurons express Nav1.2.

A learning-induced, motor-related, projection-specific signal from S1 to S2 accompanies reward-based-learning of a goal-directed sensorimotor transformation of whisker sensation into licking motor output.

Neurons called lobula columnar cells help fruit flies respond appropriately to specific visual cues, such as those signaling an approaching predator.

FGFRs regulate multipolar cortical neuron orientation and the morphological change into bipolar cells in vivo under the control of N-Cadherin and the extracellular matrix protein Reelin.

Ablation of olfactory projection neurons in adult mice triggers sprouting of the apical dendrite of remaining neurons towards multiple nearby glomeruli and disrupts the odor map.

Transsynaptic viral tracing reveals that neurons in the superior colliculus employ projection specific rules to the sampling of retinal inputs, directing distinct visual features to different downstream targets.

A novel mechanism describes how tonic activation of nicotinic acetylcholine receptors can modulate the timing of striatal output by priming feedforward inhibition.

Aberrant striatal signaling does not induce drastic changes in the spontaneous discharge rate and pattern of the striatal projection neurons in Parkinson’s disease and Dystonia.

Drosophila genetics and behavior reveal that oxidative stress induced axonal degeneration in a single class of neurons drives the functional decline of an entire neural network and the behavior it controls.

In mouse models of Huntington's disease, striatal spiny projection neurons up-regulate dendritic potassium channels, which impairs their normal function, but a zinc finger gene therapy can reverse this deficit.