Positive feedback between contractile ring myosin and compression-driven cortical flow can explain the exponential accumulation of contractile ring components and constriction rate acceleration that ensures timely cell separation during cytokinesis.

The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.

A bulk barcoded quantitative trait locus approach increases the power and resolution of genotype-phenotype mapping in yeast, revealing that the genetic architecture of 18 complex traits is highly polygenic, and is characterized by widespread epistatic interactions and pleiotropic effects.

Electrophysiology experiments with genetic and pharmacological manipulations identify a role for astrocyte GluN2C NMDA receptors in maintaining the broad range of presynaptic strengths, which is suggested by numerical simulations to enhance the expression of synaptic plasticity.

Molecular genetics identifies a novel microglial pathway essential for mouse brain development and a previously unknown anti-inflammatory activity of monomeric amyloid β that activates this pathway.

The organic insecticide spinosad severely impacts metabolism, the cell biology, and the visual system of the model insect Drosophila, suggesting that it poses a threat to other non-pest insect exposed to it in the field.

Neutral tagging and detailed analysis of bacterial growth kinetics can quantify the mechanisms of colonization resistance in differently colonized animals.

A spatial analysis of auditory and non-auditory properties of excitatory and inhibitory neurons in the mouse dorsal inferior colliculus defines the border between the lateral and the dorsal cortex.

Two different forms of brain plasticity require astrocytes and show different action mechanisms at enthorrinal cortex hippocampal synapses.

The association of Rad52 with Rad51, while not critical for Rad51 filament formation, is crucial to protect Rad51 filaments from Srs2 translocase activity through the association of Rad52 with complete Rad51 filaments.