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A novel strategy is presented for quantitatively measuring protein-DNA and protein-protein interactions that regulate transcription in living cells.

The first zygotic genes are transcribed without RNA polymerase II pausing from a TATA-enriched promoter.

SND1 has m6A-reading ability and is essential for Kaposi's sarcoma-associated lytic replication.

The crystal structure of Thermus transcription activation complexes containing the transcriptional activator CarD reveals a new mechanism for the activation of transcription.

Differential binding kinetics of a master regulator to its target promoters can prevent spontaneous cell fate loss in a Caenorhabditis elegans neuron whose fate is controlled by a reversible switch.

Functional analyses provide evidence for a complex Nod factor signalling where NFRe is necessary for maintaining an optimal symbiotic signalling in the susceptible root zone, and initiation of nodule primordia on the expanding root system.

Active DNA demethylation at some defence gene promoters is causal for DNA binding of WRKY transcription factors as well as for transcriptional activation of these genes during plant immune response.

The architecture of a gene regulatory network determines the effect of evolutionary changes in transcription factor binding.

The transcription machinery is required for the disassembly of the promoter-proximal H2A.Z nucleosome, contributing to the constitutive histone turnover at yeast promoters.

A conserved element in the flavivirus genomic 5′ terminus switches its conformation in response to long-range RNA interactions, and thereby regulates the dynamic recruitment of viral replicase for efficient viral RNA replication.