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    1. Immunology and Inflammation

    B cells suppress medullary granulopoiesis by an extracellular glycosylation-dependent mechanism

    Eric E Irons, Melissa M Lee-Sundlov ... Joseph TY Lau
    B cells regulate production of neutrophils by a novel mechanism by releasing ST6Gal-1, an active sialyltransferase, that suppresses granulopoiesis.
    1. Genetics and Genomics

    Genetic and environmental perturbations lead to regulatory decoherence

    Amanda Lea, Meena Subramaniam ... Julien F Ayroles
    Infection and metabolic syndrome lead to a loss of molecular regulation, and changes in molecular correlations are under genetic control as revealed by the presence of correlation quantitative trait loci.
    1. Stem Cells and Regenerative Medicine

    Long-term live imaging of the Drosophila adult midgut reveals real-time dynamics of division, differentiation and loss

    Judy Lisette Martin, Erin Nicole Sanders ... Lucy Erin O'Brien
    A new platform for imaging live Drosophila adults yields vivid movies of the midgut over prolonged time scales, opening the door to the real-time study of organ renewal dynamics in a near-native context.
    1. Neuroscience

    Systematic examination of low-intensity ultrasound parameters on human motor cortex excitability and behavior

    Anton Fomenko, Kai-Hsiang Stanley Chen ... Robert Chen
    Transcranial low-intensity ultrasound applied in block design and at low duty cycles and longer sonication durations can safely and non-invasively suppress human motor-evoked potentials, possibly via GABA-A-mediated inhibitory pathways.
    1. Neuroscience

    A novel Drosophila injury model reveals severed axons are cleared through a Draper/MMP-1 signaling cascade

    Maria D Purice, Arpita Ray ... Mary A Logan
    An unbiased transcriptional profiling screen reveals the secreted matrix metalloproteinase MMP-1 is a transcriptional target of the ensheathing glial receptor Draper following acute axon injury in adult Drosophila.
    1. Neuroscience

    Altered visual cortex excitatory/inhibitory ratio following transient congenital visual deprivation in humans

    Rashi Pant, Kabilan Pitchaimuthu ... Brigitte Röder
    Revised
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    1. Neuroscience

    When and why does motor preparation arise in recurrent neural network models of motor control?

    Marine Schimel, Ta-Chu Kao, Guillaume Hennequin
    A computational model shows that preparation arises as an optimal control strategy in input-driven recurrent neural networks performing a delayed-reaching task.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Resistome diversity in cattle and the environment decreases during beef production

    Noelle R Noyes, Xiang Yang ... Keith E Belk
    Interventions in feedlots and abattoirs place selective pressure on the beef cattle resistome, which differentially impacts the public health risk of antimicrobial resistance from beef production sources.
    1. Developmental Biology

    Chiral cell sliding drives left-right asymmetric organ twisting

    Mikiko Inaki, Ryo Hatori ... Hisao Honda
    Left-right asymmetric rotation of the Drosophila hindgut is driven by "cell sliding," a novel cellular behavior induced by chiral cell deformation, in which cells change their position relative to subjacent neighbors as sliding directionally.
    1. Immunology and Inflammation

    Complex subsets but redundant clonality after B cells egress from spontaneous germinal centers

    Carlos Castrillon, Lea Simoni ... Michael C Carroll
    In an autoimmune environment B cells mature from spontaneous germinal centers into transcriptomically and phenotypically diverse memory and antibody-secreting cells but maintaining shared clonal and potential self-reactive specificities which has important implications for pathogenic cell targeted depletion.