826 results found
    1. Cancer Biology

    A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer

    Chen Yang, Hailin Zhang ... Hui Wang
    Computational and experimental analyses show that homoharringtonine may be repurposed as an agent for the treatment and prevention of liver cancer.
    1. Genetics and Genomics

    Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994

    Aline Jelenkovic, Yoon-Mi Hur ... Karri Silventoinen
    Genetic variance of adult human height shows a generally increasing trend across the birth-year cohorts but heritability estimates do not present any clear pattern of secular changes over a century.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    How subtle changes in 3D structure can create large changes in transcription

    Jordan Yupeng Xiao, Antonina Hafner, Alistair N Boettiger
    Promoter futile cycles can explain how subtle differences in genome folding sometimes generate large difference in gene expression.
    1. Neuroscience

    Altered visual cortex excitatory/inhibitory ratio following transient congenital visual deprivation in humans

    Rashi Pant, Kabilan Pitchaimuthu ... Brigitte Röder
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction

    Jacob M Winter, Heidi L Fresenius ... Jared Rutter
    A common genomic deletion in various human cancers disrupts mitochondrial protein homeostasis in a way that might be targeted by existing drugs.
    1. Epidemiology and Global Health

    From multiplicity of infection to force of infection for sparsely sampled Plasmodium falciparum populations at high transmission

    Qi Zhan, Kathryn E Tiedje ... Mercedes Pascual
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Ultrastructural sublaminar-specific diversity of excitatory synaptic boutons in layer 1 of the adult human temporal lobe neocortex

    Astrid Rollenhagen, Akram Sadeghi ... Joachim HR Lübke
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Cancer Biology

    Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

    Denise Ragusa, Chun-Wai Suen ... Cristina Pina
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Inadequate
    1. Cancer Biology

    The integration of Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion

    Apsra Nasir, Sharon Camacho ... Gray W. Pearson
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid

Refine your results by:

Type
Research categories